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human GPR68 protein

RefSeq NM_003485

Also Known As:

GPR68 protein, human; G-protein-coupled receptor 68; G-protein-coupled receptor 68, human; OGR1 protein, human

Networked: 6 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Membrane Proteins: 10078
    - Cell Surface Receptors: 2125
      - G-Protein-Coupled Receptors: 4701
        human GPR68 protein: 6

Experts

1.	Fang, Jing: 2 articles (10/2021 - 01/2020)
2.	Cao, L: 1 article (02/2022)
3.	Chen, X H: 1 article (02/2022)
4.	Ding, Y M: 1 article (02/2022)
5.	Gao, R: 1 article (02/2022)
6.	Zhou, M J: 1 article (02/2022)
7.	Park, Isaac: 1 article (10/2021)
8.	Phan, Tra Mi: 1 article (10/2021)
9.	Araki, Kenichiro: 1 article (01/2021)
10.	Gantumur, Dolgormaa: 1 article (01/2021)

Related Diseases

1.	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 01/01/2020 - "Our previous study revealed that expression of G protein-coupled receptor 68 (GPR68) was upregulated in MDSL cells, a cell line representing myelodysplastic syndromes (MDS), in response to lenalidomide (LEN), and mediated a calcium/calpain proapoptotic pathway. "
2.	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 10/11/2021 - "We have found that lenalidomide-mediated degradation of IKZF1 leads to activation of the G protein-coupled receptor 68 (GPR68)/calcium/calpain pro-apoptotic pathway and inhibition of the regulator of calcineurin 1 (RCAN1)/calcineurin pro-survival pathway in MDS and acute myeloid leukemia (AML). "
3.	Inflammation (Inflammations) 01/01/2021 - "A search for the underlying cause of the attenuation of heart disorder in Clk/Clk mice with 5/6 nephrectomy (5/6Nx) led to identification of the monocytic expression of G protein-coupled receptor 68 (GPR68) as a risk factor of CKD-induced inflammation and fibrosis of heart. "
4.	Hepatocellular Carcinoma (Hepatoma) 01/01/2021 - "Conophylline Inhibits Hepatocellular Carcinoma by Inhibiting Activated Cancer-associated Fibroblasts Through Suppression of G Protein-coupled Receptor 68."
5.	Heart Diseases (Heart Disease) 01/01/2021 - "A search for the underlying cause of the attenuation of heart disorder in Clk/Clk mice with 5/6 nephrectomy (5/6Nx) led to identification of the monocytic expression of G protein-coupled receptor 68 (GPR68) as a risk factor of CKD-induced inflammation and fibrosis of heart. "

Related Drugs and Biologics

1.	Calpain
2.	Calcium
3.	Lenalidomide (CC 5013)
4.	Calcineurin
5.	Proteins (Proteins, Gene)
6.	Fluorouracil (Carac)
7.	conophylline

Related Therapies and Procedures

1.	Nephrectomy
2.	Drug Therapy (Chemotherapy)
3.	TP protocol