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miliusol

from Miliusa balansae; structure in first source

Also Known As:

9-hydroxy-1-(2,6-dimethylhepta-1,5-dienyl)-3,6-2-oxa-spiro(4.5)dec-7-ene

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Carboxylic Acids: 973
  - Carbocyclic Acids
    - Phenylacetates: 3
      - Homogentisic Acid: 299
        miliusol: 3

Experts

1.	Guan, Yi-Fu: 1 article (01/2019)
2.	Lam, Chu Shing: 1 article (01/2019)
3.	Lee, Kwan Ming: 1 article (01/2019)
4.	Lee, Magnolia Muk Lan: 1 article (01/2019)
5.	Liu, Kang-Lun: 1 article (01/2019)
6.	Pan, Wen-Hui: 1 article (01/2019)
7.	Tai, William Chi Shing: 1 article (01/2019)
8.	The Son, Ninh: 1 article (01/2019)
9.	Tsang, Siu Wai: 1 article (01/2019)
10.	Wong, Wing Yan: 1 article (01/2019)

Related Diseases

1.	Neoplasms (Cancer) 01/01/2019 - "(+)-Miliusol (72) stimulated in vivo anticancer experiment against HCT116 xenograft mouse tumor following the p21-dependent induction of cellular senescence mechanism." 01/01/2019 - "When extrapolated to various carcinoma xenograft mouse models, miliusol (1) and its derivatives 20, 26, and 27 (7.5-40 mg/kg) were demonstrated with tumor inhibitory efficacy comparable or even superior to the mainstay chemotherapeutics paclitaxel or fluorouracil. "
2.	Stomach Neoplasms (Stomach Cancer) 11/01/2023 - "Compound 11 demonstrated more potent cytotoxic activity than the known miliusol (1) in stomach cancer cells though its structure contains an unconjugated 1, 4-diketone system, which added a new structure-activity feature to miliusanes. "
3.	Carcinoma (Carcinomatosis) 01/01/2019 - "When extrapolated to various carcinoma xenograft mouse models, miliusol (1) and its derivatives 20, 26, and 27 (7.5-40 mg/kg) were demonstrated with tumor inhibitory efficacy comparable or even superior to the mainstay chemotherapeutics paclitaxel or fluorouracil. "

Related Drugs and Biologics

1.	Paclitaxel (Taxol)
2.	Fluorouracil (Carac)