ZK 216348

ZK-209614 is the racemic mixture, ZK-216348 is the (+)-isomer, and ZK-216347 is the (-)-isomer; a selective glucocorticoid receptor agonist; structure in first source

Also Known As:

ZK 209614; ZK 216347; ZK-209614; ZK-216347; ZK-216348; ZK209614; ZK216347; ZK216348

Networked: 3 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Oxazines: 9
    - Benzoxazines: 58
      - ZK 216348: 3
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzoxazines: 58
      - ZK 216348: 3
    - Benzofurans: 26
      - ZK 216348: 3

Experts

1.	Grunwitz, Christian R: 1 article (04/2012)
2.	Kaminski, Bettina M: 1 article (04/2012)
3.	Radeke, Heinfried H: 1 article (04/2012)
4.	Reuter, Kerstin C: 1 article (04/2012)
5.	Stein, Jürgen: 1 article (04/2012)
6.	Steinhilber, Dieter: 1 article (04/2012)
7.	Aono, Hiroyuki: 1 article (08/2011)
8.	Hagiwara, Yumi: 1 article (08/2011)
9.	Imamura-Takai, Miwa: 1 article (08/2011)
10.	Kato, Masatomo: 1 article (08/2011)

Related Diseases

1.	Inflammation (Inflammations) 04/01/2012 - "Our results showed that, comparable with Dex, treatment with CpdA and ZK216348 reduced the severity of wasting disease, macroscopic and microscopic damage, and colonic inflammation. " 01/06/2004 - "In a murine model of skin inflammation, ZK 216348 showed antiinflammatory activity comparable to prednisolone for both systemic and topical application. "
2.	Wasting Syndrome (Wasting Disease) 04/01/2012 - "Our results showed that, comparable with Dex, treatment with CpdA and ZK216348 reduced the severity of wasting disease, macroscopic and microscopic damage, and colonic inflammation. "
3.	Edema (Dropsy) 08/01/2011 - "When given as eyedrops, ZK209614 and betamethasone phosphate each had an inhibitory effect on edema weight in the rat carrageenan-induced conjunctivitis model. "
4.	Diabetes Mellitus 01/06/2004 - "Based on these findings, ZK 216348 should have a lower risk, e.g., for induction of diabetes mellitus. "
5.	Allergic Conjunctivitis (Giant Papillary Conjunctivitis) 08/01/2011 - "In the rat allergic conjunctivitis model, ZK209614 reduced the elevated vascular permeability at a concentration of 0.1%. " 08/01/2011 - "To evaluate anti-inflammatory and antiallergic activities in vivo, ZK209614 and betamethasone phosphate were tested in the carrageenan-induced conjunctivitis model and allergic conjunctivitis model in rats. "

Related Drugs and Biologics

1.	Anti-Allergic Agents (Antiallergic Agents)
2.	Prednisolone (Predate)
3.	Ophthalmic Solutions (Eye Drops)
4.	Chlorides
5.	Carrageenan
6.	ethylammonium
7.	2- (4- acetoxyphenyl)- 2- chloro- N- methylethylamine
8.	betamethasone sodium phosphate