HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

HS 131

a melanocortin 4 receptor antagonist; structure in first source

Also Known As:

HS-131; HS131 peptide

Networked: 2 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Polycyclic Compounds: 6
- Macrocyclic Compounds: 15
  - Cyclic Peptides: 530
    - HS 131: 2
Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Cyclic Peptides: 530
    - HS 131: 2

Experts

1.	Chen, Jiegen: 1 article (01/2022)
2.	Haystead, Timothy: 1 article (01/2022)
3.	Hughes, Philip: 1 article (01/2022)
4.	Kim, Shin Hyung: 1 article (01/2022)
5.	Nackley, Andrea G: 1 article (01/2022)
6.	Scarneo, Scott A: 1 article (01/2022)
7.	Wang, Yaomin: 1 article (01/2022)
8.	Yang, Kelly W: 1 article (01/2022)
9.	Zhang, Xin: 1 article (01/2022)

Related Diseases

1.	Arthritis (Polyarthritis) 10/27/2022 - "Moreover, despite rapid hepatobiliary clearance, HS-131 demonstrated efficacy in reducing the mean clinical score in the CIA arthritis model. "
2.	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 10/27/2022 - "Following injection of HS-131 in mouse models of human rheumatoid arthritis and inflammatory bowel disease, we detected localization of the probe at sites of active disease, consistent with immune cell invasion. "
3.	Pain (Aches) 01/01/2022 - "Treatment of mice with the selective eHsp90 inhibitor HS-131 (10 nmol) significantly reversed CFA-induced mechanical pain, thermal heat pain, and hind paw edema. "
4.	Edema (Dropsy) 01/01/2022 - "Treatment of mice with the selective eHsp90 inhibitor HS-131 (10 nmol) significantly reversed CFA-induced mechanical pain, thermal heat pain, and hind paw edema. "
5.	Rheumatoid Arthritis 10/27/2022 - "Following injection of HS-131 in mouse models of human rheumatoid arthritis and inflammatory bowel disease, we detected localization of the probe at sites of active disease, consistent with immune cell invasion. "