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mouse Itch protein

RefSeq XM_192925

Also Known As:

Itch protein, mouse; Aip4 protein, mouse; E3 ubiquitin-protein ligase Itch; Itchy protein, mouse; itchy, E3 ubiquitin protein ligase, mouse

Networked: 7 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Ligases: 5553
    - Ubiquitin-Protein Ligase Complexes
      - Ubiquitin-Protein Ligases: 3432
        mouse Itch protein: 7

Experts

1.	Ma, Ti-Dong: 1 article (10/2022)
2.	Xia, Ren-Peng: 1 article (10/2022)
3.	Xu, Guang: 1 article (10/2022)
4.	Zhao, Fan: 1 article (10/2022)
5.	Zhou, Chong-Gao: 1 article (10/2022)
6.	Zou, Chan-Juan: 1 article (10/2022)
7.	Chen, Wei-Wei: 1 article (01/2022)
8.	Chu, Xiao-Yuan: 1 article (01/2022)
9.	Fang, Rong: 1 article (01/2022)
10.	Huang, Gui-Chun: 1 article (01/2022)

Related Diseases

1.	Neoplasms (Cancer) 10/01/2022 - "Research suggested critical roles for circular RNA (circRNA) itchy E3 ubiquitin protein ligase (ITCH) in gastrointestinal malignancies progression. " 01/01/2018 - "Circ-ITCH is a circRNA generated from several exons of itchy E3 ubiquitin protein ligase (ITCH) and tumor suppressor served as a sponge for certain miRNAs targeting their parental transcripts of ITCH. " 11/01/2022 - "Expression levels of CXCR4 and its regulators hypoxia-inducible factor 1-alpha (HIF-1α), tristetraprolin (TTP), human antigen R (HuR), itchy E3 ubiquitin protein ligase (ITCH), miR-302a and miR-494 were determined and their associations with tumor recurrence and disease-free survival were analyzed. "
2.	Hypoxia (Hypoxemia) 01/01/2022 - "Here, we evaluated Itchy E3 ubiquitin protein ligase (ITCH) expression in LC cells following hypoxia treatment. " 11/01/2022 - "Expression levels of CXCR4 and its regulators hypoxia-inducible factor 1-alpha (HIF-1α), tristetraprolin (TTP), human antigen R (HuR), itchy E3 ubiquitin protein ligase (ITCH), miR-302a and miR-494 were determined and their associations with tumor recurrence and disease-free survival were analyzed. "
3.	Melanoma (Melanoma, Malignant) 04/01/2020 - "Furthermore, we revealed that miR-520f could interact with circular RNA Itchy E3 ubiquitin protein ligase (ITCH) 3'-untranslated region and suppress ITCH expression in human melanoma cells. "
4.	Lung Diseases (Lung Disease) 01/01/2019 - "We report a 23 year old female with biallelic truncating variants in the ITCH (Itchy E3 Ubiquitin protein ligase, mouse homolog of; OMIM60649) gene associated with marked short stature, severe early onset chronic lung disease resembling asthma, dysmorphic facial features, and symmetrical camptodactyly of the fingers but normal intellect. "
5.	Autoimmune Diseases (Autoimmune Disease) 01/01/2019 - "Mutations in the itchy E3 ubiquitin protein ligase (ITCH) gene (located on chromosome 20q11.22) can lead to a deficiency of the encoded protein, resulting in increased T-cell activity with lack of immune tolerance and manifestation of a complex systemic autoimmune disease. "

Related Drugs and Biologics

1.	Circular RNA
2.	Tristetraprolin
3.	MicroRNAs (MicroRNA)
4.	Proteins (Proteins, Gene)
5.	Antigens
6.	thiamine triphosphorate (TTP)