vernolide

from Vernonia colorata (Compositae); RN given for (1aR-(1aR*,4Z,5aR*,8aR*,9S*,10aR*,11R*))-isomer; structure in first source

Networked: 3 relevant articles (0 outcomes, 1 trials/studies)

1.	Boonsombat, Jutatip: 2 articles (01/2022 - 11/2019)
2.	Chawengrum, Pornsuda: 2 articles (01/2022 - 11/2019)
3.	Keeratichamroen, Siriporn: 2 articles (01/2022 - 11/2019)
4.	Lirdprapamongkol, Kriengsak: 2 articles (01/2022 - 11/2019)
5.	Ruchirawat, Somsak: 2 articles (01/2022 - 11/2019)
6.	Svasti, Jisnuson: 2 articles (01/2022 - 11/2019)
7.	Thongnest, Sanit: 2 articles (01/2022 - 11/2019)
8.	Ornnork, Narittira: 1 article (01/2022)
9.	Sirirak, Jitnapa: 1 article (01/2022)
10.	Sornprachum, Thiwaree: 1 article (01/2022)

1.	Lung Neoplasms (Lung Cancer) 01/01/2022 - "The present study demonstrated the anti‑proliferative effect and apoptosis‑inducing activity of three sesquiterpene lactones isolated from Gymnanthemum extensum, vernodalin (VDa), vernolepin (VLe) and vernolide (VLi), on A549 human lung cancer cells. "
2.	Prostatic Neoplasms (Prostate Cancer) 07/24/2015 - "Vernolide (1) emerged as a potent inhibitor of STAT3 and NF-κB and showed cytostatic activity toward the prostate cancer cell line DU45, arresting the cell cycle at the S phase. "
3.	Neoplasms (Cancer) 11/01/2019 - "Vernolide has potent broad-spectrum cytotoxicity with IC50 values in the range of 0.91-13.84 μM, against all ten cancer cell lines. " 11/01/2019 - "Vernodalidimer L, a sesquiterpene lactone dimer from Vernonia extensa and anti-tumor effects of vernodalin, vernolepin, and vernolide on HepG2 liver cancer cells."
4.	Liver Neoplasms (Liver Cancer) 11/01/2019 - "Our results indicated that vernodalin, vernolepin, and vernolide have potential to be used as lead compounds in the development of a therapeutic natural product for treatment of liver cancer." 11/01/2019 - "Vernodalidimer L, a sesquiterpene lactone dimer from Vernonia extensa and anti-tumor effects of vernodalin, vernolepin, and vernolide on HepG2 liver cancer cells."