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lupeol synthase

catalyzes cyclization of oxidosqualene to lupeol

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Isomerases: 463
    - Intramolecular Transferases: 3
      - lupeol synthase: 2

Experts

1.	Azizi, Ali: 1 article (09/2021)
2.	Mirjalili, Mohammad Hossein: 1 article (09/2021)
3.	Rigano, Maria Manuela: 1 article (09/2021)
4.	Sarikhani, Hassan: 1 article (09/2021)
5.	Tavan, Mansoureh: 1 article (09/2021)

Related Diseases

1.	Polyploidy 09/01/2021 - "Although a significant decrease in ursolic acid content was observed in polyploids, betulinic acid content associated with the expression levels of genes encoding enzymes being active in triterpene biosynthesis such as squalene epoxidase (SQE) and lupeol synthase (LUS). "
2.	Gastroesophageal Reflux (GERD) 01/16/2023 - "A total of six differentially expressed enzymes were found in the main pathway of gossypol synthesis-sesquiterpene and triterpene biosynthesis (map00909): lupeol synthase (LUP1, EC:5.4.99.41), beta-amyrin synthase (LUP2, EC:5.4.99.39), squalene monooxygenase (SQLE, EC:1.14.14.17), squalene synthase (FDFT1, EC:2.5.1.21), (-)-germacrene D synthase (GERD, EC:4.2.3.75), ( +)-delta-cadinene synthase (CADS, EC:4.2.3.13). "

Related Drugs and Biologics

1.	Squalene Monooxygenase (Squalene Epoxidase)
2.	Triterpenes
3.	Enzymes
4.	Farnesyl-Diphosphate Farnesyltransferase (Squalene Synthase)
5.	Sesquiterpenes
6.	Gossypol
7.	Ursolic Acid
8.	Betulinic Acid
9.	germacrene D synthase
10.	delta-cadinene synthase