protax

a cephem prodrug of taxol, synthesized by substituting the C-3' position of cephalothin with 2'-(gamma-aminobutyryl)taxol; structure given in first source

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Asada, Yuka: 1 article (01/2021)
2.	Chriqui, Jamie F: 1 article (01/2021)
3.	Pipito, Andrea: 1 article (01/2021)
4.	Taher, Sabira: 1 article (01/2021)
5.	Barry, Colleen L: 1 article (05/2014)
6.	Gollust, Sarah E: 1 article (05/2014)
7.	Jou, Judy: 1 article (05/2014)
8.	Niederdeppe, Jeff: 1 article (05/2014)

Related Diseases

1.	Obesity 05/01/2014 - "The protax messages most frequently mentioned by respondents were reinvesting tax revenue into health-related programs and linking SSB consumption to health outcomes such as obesity and diabetes. "
2.	Neoplasms (Cancer) 04/01/1995 - "PROTAX is approximately 10-fold less toxic than taxol against SK-BR-3 breast tumor cells in vitro but has activity approaching that of taxol following prolonged activation with a fusion protein comprising beta-lactamase fused to a tumor-targeting antibody fragment. "
3.	Confusion (Bewilderment) 01/01/2021 - "Protax documents (n = 33) highlighted SSB consumption and health associations and countered antitax messaging; antitax documents (n = 10) focused on misinformation and sowing public confusion. "
4.	Breast Neoplasms (Breast Cancer) 04/01/1995 - "PROTAX is approximately 10-fold less toxic than taxol against SK-BR-3 breast tumor cells in vitro but has activity approaching that of taxol following prolonged activation with a fusion protein comprising beta-lactamase fused to a tumor-targeting antibody fragment. "

Related Drugs and Biologics

1.	Paclitaxel (Taxol)
2.	Proteins (Proteins, Gene)
3.	Immunoglobulin Fragments
4.	beta-Lactamases (beta-Lactamase)