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CH 5450

Also Known As:

CH-5450; Z-Ile-Glu-Pro-Phe-CO2Me

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Oligopeptides: 519
    - CH 5450: 1

Related Diseases

1.

Sexually Transmitted Diseases (Sexually Transmitted Disease)

07/01/1997 - "On the other hand, STI (200 microg ml(-1)) and CH 5450 (10 microM) added separately, depressed the (Pro11-,D-Ala12)-AI-induced contractions to 34 +/- 5% (n=6) and 24 +/- 4% (n=6), respectively. "
07/01/1997 - "The combination of enalaprilat and STI or enalaprilat and CH 5450 did not produce any further inhibition. "
07/01/1997 - "However, the combination of enalaprilat and STI reduced the AI-induced contractions to 19 +/- 5% (n=6), and the combination of enalaprilat and CH 5450 caused an almost complete inhibition of the AI-induced contractions to 1+/-1% (n=6). "
07/01/1997 - "This response was reduced to 36 +/- 3% (n=8) by the ACE-inhibitor enalaprilat (10 microM), while pretreatment with soybean trypsin inhibitor (STI 200 microg ml(-1)) or CH 5450 (10 microM) had no effect. "

Related Drugs and Biologics

1.	Enalaprilat (Vasotec)
2.	Trypsin Inhibitors
3.	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)