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KU 14R

an antagonist of the islet imidazoline receptor; structure given in first source

Also Known As:

2-(2-ethyl-2,3-dihydro-2-benzofuranyl)-2-imidazole; KU-14R; KU14R

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Imidazoles: 150
      - KU 14R: 2
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzofurans: 26
      - KU 14R: 2

Experts

1.	Cheng, Juei-Tang: 1 article (10/2017)
2.	Hsu, Chia-Chen: 1 article (10/2017)
3.	Lin, Jenshinn: 1 article (10/2017)
4.	Lin, Mang Hung: 1 article (10/2017)
5.	Wu, Ming Chang: 1 article (10/2017)

Related Diseases

1.	Hypoglycemia (Reactive Hypoglycemia) 10/01/2017 - "Additionally, KU14R dose-dependently inhibited the morin-induced effects, including hypoglycemia and the increase in insulin secretion and plasma C-peptide levels, in diabetic rats. "
2.	Asthma (Bronchial Asthma) 07/31/2022 - "Compared with the control group, 100 fxmol and L1 Efaroxan promoted insulin secretion (P <0.01), and administration of the MUC5AC antagonist KU14R significantly inhibited the effect of MUC5AC.Western blot showed that the protein expression levels of β-catenin, c-Myc and cyclin D1 in ASMC of the obese asthma group were significantly higher than those of the control group (P <0.05), while the protein expression level of GSK-3β was lower than Control group (P <0.05). "

Related Drugs and Biologics

1.	Catenins
2.	Cyclin D1
3.	Proteins (Proteins, Gene)
4.	C-Peptide
5.	efaroxan
6.	morin