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mepanipyrim
Also Known As:
N-(4-methyl-6-prop-1-ynylpyrimidin-2-yl)aniline
Networked:
8
relevant articles (
0
outcomes,
1
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Pyrimidines: 510
mepanipyrim: 8
Experts
1.
Food Safety Commission of Japan
: 1 article (03/2016)
Related Diseases
1.
Cardiotoxicity
03/01/2023 - "
In this study, we aimed to investigate mepanipyrim-induced cardiotoxicity in zebrafish (Danio rerio) larvae.
"
03/01/2023 - "
Studies of mepanipyrim-induced toxicity in organisms are still scarce, especially studies on cardiotoxicity.
"
03/01/2023 - "
In conclusion, the AhR agonist mepanipyrim could induce cardiotoxicity in a novel unreported AhR-regulated manner, which could specifically affect the expression of COX family genes involved in the mitochondrial oxidative respiratory chain.
"
03/01/2023 - "
We found that mepanipyrim could induce cardiotoxicity by altering the heart rate and cardiomyocyte diameter of larvae.
"
03/01/2023 - "
Mepanipyrim induces cardiotoxicity of zebrafish (Danio rerio) larvae via promoting AhR-regulated COX expression pathway.
"
2.
Fatty Liver
01/01/1999 - "
These results together suggested that fatty liver induced by mepanipyrim results mainly from the inhibition of the transport of hepatic VLDL from the Golgi to the cell surface.
"
01/01/1999 - "
To clarify the mechanism by which mepanipyrim induces fatty liver, morphological and biochemical effects of mepanipyrim on the movement of VLDL in rat liver and in the primary culture of rat hepatocytes were investigated.
"
08/01/1998 - "
These results suggest that the fatty liver induced by mepanipyrim would be due to the inhibition of hepatic VLDL synthesis or its secretion into the blood.
"
08/01/1998 - "
Our preceding paper reported that mepanipyrim, a new fungicide, induced fatty liver in the rat.
"
08/01/1998 - "
Mepanipyrim induces fatty liver in rats but not in mice and dogs.
"
3.
Mycoses (Diseases, Fungus)
02/01/2023 - "
Mepanipyrim, an anilinopyrimidine fungicide, has been extensively used to prevent fungal diseases in fruit culture.
"
04/01/2023 - "
Mepanipyrim and cyprodinil are widely used to control and/or prevent fungal diseases in fruit culture.
"
4.
Vesicular Stomatitis
10/01/1996 - "
Mepanipyrim, N-(4-methyl-6-prop-1-ynylpyrimidin-2-yl)aniline, diminished the cell surface expression of envelope glycoproteins of Newcastle disease and vesicular stomatitis viruses at concentrations where their synthesis was not profoundly affected.
"
5.
Newcastle Disease
10/01/1996 - "
Mepanipyrim, N-(4-methyl-6-prop-1-ynylpyrimidin-2-yl)aniline, diminished the cell surface expression of envelope glycoproteins of Newcastle disease and vesicular stomatitis viruses at concentrations where their synthesis was not profoundly affected.
"
Related Drugs and Biologics
1.
mepanipyrim
2.
Pesticides
3.
VLDL Lipoproteins
4.
Glycoproteins (Glycoprotein)
5.
Electron Transport Complex IV (Cytochrome c Oxidase)
6.
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide
7.
cyprodinil