C 1310

an imidazoacridinone; arrests cell-cycle progression in the G2 phase of L1210 cells; structure given in first source

Also Known As:

5-((2-(diethylamino)ethyl)amino)-8-hydroxy-1-methyl-6H-imidazo(4,5,1-de)acridin-6-one; C-1310; C1310

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 3-Ring Heterocyclic Compounds
    - Acridines: 325
      - Aminoacridines: 3
        C 1310: 4

Experts

1.	Baroudi, Olfa: 1 article (10/2018)
2.	Belaiba, Fadoua: 1 article (10/2018)
3.	Benammar El gaaied, Amel: 1 article (10/2018)
4.	Bidet, Yannick: 1 article (10/2018)
5.	Bignon, Yves Jean: 1 article (10/2018)
6.	Boussetta, Sami: 1 article (10/2018)
7.	Medimegh, Imene: 1 article (10/2018)
8.	Mezlini, Amel: 1 article (10/2018)
9.	Benjaafar, Noureddine: 1 article (06/2017)
10.	Bouguenouch, Laila: 1 article (06/2017)

Related Diseases

1.	Breast Neoplasms (Breast Cancer) 04/13/2023 - "Our findings suggest that BRCA1 c.5309G>T and BRCA2 c.1310_1313delAAGA mutations may have a strong founder and/or recurrent effect on breast cancer among the Northeastern Moroccan population. " 04/13/2023 - "Screening for the germline mutations c.5309G>T and BRCA2 c.1310_1313delAAGA was performed by sequencing on a total of 184 breast cancer (BC) patients originated from the Northeastern region of Morocco. " 04/13/2023 - "Increased prevalence of the founder BRCA1 c.5309G>T and recurrent BRCA2 c.1310_1313delAAGA mutations in breast cancer families from Northerstern region of Morocco: evidence of geographical specificity and high relevance for genetic counseling." 10/26/2018 - "Four deleterious mutations were found in BRCA2 gene including a novel frame-shift mutationc.9382_9383dup in a patient with familial breast cancer and three other frame-shift mutations c.6591_6592del, c.1310_1313del and c.7654dup in patients with sporadic breast cancer.These"
2.	Ovarian Neoplasms (Ovarian Cancer) 06/02/2017 - "High frequency of the recurrent c.1310_1313delAAGA BRCA2 mutation in the North-East of Morocco and implication for hereditary breast-ovarian cancer prevention and control."
3.	Neoplasms (Cancer) 04/13/2023 - "Therefore, we believe that BRCA1 c.5309G>T and BRCA2 c.1310_1313delAAGA mutations have to be included in the array of tests aimed at revealing cancer syndrome carriers among subjects of Moroccan origin."
4.	Squamous Cell Carcinoma of Head and Neck 10/30/2008 - "Moreover, we investigated the association between 5 single nucleotide polymorphisms (SNPs) in the homologous recombination DNA repair pathway (XRCC3 c.-1843 A>G, XRCC3 c.562-14 A>G, XRCC3 c.722 C>T, Rad51 c.-3429 G>C, Rad51 c.-3392 G>T) and 4 SNPs in the non- homologous end joining DNA repair pathway (Lig4 c.26 C>T, Lig4 c.1704 T>C, Ku70 c.-1310 C>G and Ku80 c.2110-2408 G>A) on one hand and the risk of the development of HNSCC on the other hand in a case- control setting in a Caucasian population. "
5.	Familial Breast Cancer 10/26/2018 - "Four deleterious mutations were found in BRCA2 gene including a novel frame-shift mutationc.9382_9383dup in a patient with familial breast cancer and three other frame-shift mutations c.6591_6592del, c.1310_1313del and c.7654dup in patients with sporadic breast cancer.These"