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filenadol
Also Known As:
1-(3',4'-methylenedioxyphenyl)-1-morpholinopropan-2-ol; d,l-erythro-1-(3',4'-methylenedioxyphenyl)-1-morpholinopropan-2-ol
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Oxazines: 9
Morpholines: 6
filenadol: 1
Related Diseases
1.
Pain (Aches)
01/01/1995 - "
Antinociceptive activity of filenadol on inflammatory pain.
"
01/01/1995 - "
The late phase of formalin-induced pain response in mice was prevented by filenadol, without affecting the oedema.
"
2.
Hyperalgesia
01/01/1995 - "
The novel analgesic filenadol (d, 1-erythro-1-(3',4'-methylenedioxyphenyl)-1- morpholinopropan-2-ol) inhibited phenyl-p-benzoquinone-induced writhing in mice with ID50 values of 68.8 (p.o.), 1.67 (i.v.) and 0.48 (i.c.v.) mg/kg. Hyperalgesia induced by arachidonic acid, PGE2 or LTB4 in this test was also decreased by filenadol (ID50 = 24.4, 3.7 and 50.1 mg/kg p.o., respectively).
"
Related Drugs and Biologics
1.
Arachidonic Acid (Vitamin F)
2.
Dinoprostone (PGE2)
3.
Leukotriene B4
4.
Formaldehyde (Formol)
5.
Analgesics (Analgesic Drugs)
6.
phenylbenzoquinone