polymeric 4,4'-diphenylmethane diisocyanate
a mixture of MDI, 2,4'-methylene-bis(phenyl isocyanate), 2,2'-methylene-bis(phenyl isocyanate), & a range of other species, including oligomers of high MW; used in making a variety of products, such as rigid & semi-rigid foams and binders
Also Known As:
polymeric MDI; polymeric methylenediphenyl diisocyanate
Networked: 2
relevant articles (0 outcomes,
2 trials/studies)
Bio-Agent Context: Research Results
Related Diseases
1. | Neoplasms (Cancer)
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2. | Hyperplasia
02/01/1994
- " In a second 13-week study with 6-week-old rats, using exposure concentrations of 0, 4.1, 8.4, and 12.3 mg polymeric MDI/m3 (95% < 5 microns) and including a 4-week recovery period, 12.3 mg/m3 induced mortality, growth retardation, severe respiratory distress, increased lung weights, degeneration and hyperplasia of the nasal epithelium, accumulations of macrophages in the lungs and mediastinal lymph nodes, and focal inflammatory changes in the lungs.(ABSTRACT TRUNCATED AT 250 WORDS)"
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