CI acid orange 3

source gives many trade names; structure in first source

Also Known As:

2-anilino-5-(2,4-dinitroanilino)benzenesulfonic acid monosodium salt; 5-((2,4-dinitrophenyl)amino)-2-(phenylamino)benzenesulfonic acid monosodium salt; Acid Fast Yellow AG; Acid Fast Yellow E5R; C.I. Acid Orange 3; CI acid orange 3 sodium salt; sodium 4-(2,4-dinitroanilino)diphenylamine-2-sulfonate

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133

Related Diseases

1.	Carcinogenesis 12/01/1988 - "NTP Toxicology and Carcinogenesis Studies of C.I. Acid Orange 3 (CAS No. 6373-74-6) in F344/N Rats and B6C3F1 Mice (Gavage Studies)." 12/01/1988 - "Toxicology and carcinogenesis studies of C.I. Acid Orange 3 (90% pure, containing 10% water for short-term studies and containing 6%-8% water and 2%-4% acetone for 2-year studies) were conducted by administering the dye in corn oil by gavage to F344/N rats and B6C3F1 mice of each sex for 14 days, 13 weeks, or 2 years. "
2.	Neoplasms (Cancer) 12/01/1988 - "Even though no squamous cell urinary bladder neoplasms have been observed in 1,665 corn oil vehicle control female B6C3F1 mice, this single neoplasm in a low dose animal was not considered to be related to the administration of C.I. Acid Orange 3. Genetic Toxicology: C.I. Acid Orange 3 was mutagenic with and without exogenous metabolic activation in Salmonella typhimurium strains TA97; TA98; and TA100; no mutagenicity was observed for strain TA1535. "
3.	Transitional Cell Carcinoma 12/01/1988 - "There was clear evidence of carcinogenic activity of C.I. Acid Orange 3 for female F344/N rats as shown by the occurrence of transitional cell carcinomas of the kidney in the 750 mg/kg group; this group had reduced survival and chemically related nonneoplastic lesions of the kidney. "
4.	Urinary Bladder Neoplasms (Bladder Cancer) 12/01/1988 - "Even though no squamous cell urinary bladder neoplasms have been observed in 1,665 corn oil vehicle control female B6C3F1 mice, this single neoplasm in a low dose animal was not considered to be related to the administration of C.I. Acid Orange 3. Genetic Toxicology: C.I. Acid Orange 3 was mutagenic with and without exogenous metabolic activation in Salmonella typhimurium strains TA97; TA98; and TA100; no mutagenicity was observed for strain TA1535. "

Related Drugs and Biologics

1.	Coloring Agents (Dyes)
2.	Corn Oil (Oil, Corn)
3.	Acetone