vinaxanthone (411F)

structure given in first source

Also Known As:

411F; SM-345431; vina-xanthone; 9H-Xanthene-1-carboxylic acid, 5,7-diacetyl-6-(5-carboxy-6,7-dihydroxy-4-oxo-4H-1-benzopyran-3-yl)-2,3-dihydroxy-9-oxo-

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 3-Ring Heterocyclic Compounds
    - Xanthenes: 65
      - Xanthones: 211
        vinaxanthone: 2

Experts

1.	Okano, Hideyuki: 2 articles (11/2017 - 01/2012)
2.	Shimmura, Shigeto: 2 articles (11/2017 - 01/2012)
3.	Tsubota, Kazuo: 2 articles (11/2017 - 01/2012)
4.	Yoshida, Satoru: 2 articles (11/2017 - 01/2012)
5.	Hatou, Shin: 1 article (11/2017)
6.	Inagaki, Emi: 1 article (11/2017)
7.	Yamazaki, Risa: 1 article (11/2017)
8.	Yamazoe, Katsuya: 1 article (11/2017)
9.	Kawakita, Tetsuya: 1 article (01/2012)
10.	Kimura, Toru: 1 article (01/2012)

Related Diseases

1.	Corneal Neovascularization 01/01/2012 - "CD31 staining was used to determine corneal neovascularization as a possible side effect of SM-345431. "
2.	Dry Eye Syndromes (Dry Eye Syndrome) 11/14/2017 - "Using a murine dry eye model, we found that topical SM-345431, a selective Sema3A inhibitor, preserved corneal sensitivity (2.3 ± 0.3 mm versus 1.4 ± 0.1 mm in vehicle control, p = 0.004) and tear volume (1.1 ± 0.1 mm versus 0.3 ± 0.1 mm in vehicle control, p < 0.001). " 11/14/2017 - "The Semaphorin 3A inhibitor SM-345431 preserves corneal nerve and epithelial integrity in a murine dry eye model."
3.	Corneal Diseases (Corneal Disease) 01/01/2012 - "Subconjunctival injections of SM-345431 promoted a robust network of regenerating nerves as well as functional recovery of corneal sensation in a mouse keratoplasty model, suggesting a novel therapeutic strategy for treating neurotrophic corneal disease."

Related Drugs and Biologics

1.	Semaphorin-3A

Related Therapies and Procedures

1.	Corneal Transplantation (Keratoplasty)
2.	Injections