TY 11345

TY-11345 is the sodium salt; structure given in first source

Also Known As:

(+-)-2-((4-methoxy-6,7,8,9-tetrahydro-5H-cyclohepta(b)pyridin-9-yl)sulfinyl)-1H-benzimidazole sodium salt; TY-11345; 5H-Cyclohepta(b)pyridine, 9-(1H-benzimidazol-2-ylsulfinyl)-6,7,8,9-tetrahydro-4-methoxy-, sodium salt

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzimidazoles: 245
      - TY 11345: 1

Related Diseases

1.	Ulcer 08/01/1993 - "In experimental ulcer models, TY-11345 prevented the formation of water-immersion stress, ethanol or indomethacin-induced gastric lesions and mepirizole-induced duodenal lesions in rats. "
2.	Peptic Ulcer (Peptic Ulcers) 08/01/1993 - "These results suggest that TY-11345 has potent antisecretory and antiulcer effects which are exerted by suppression of H+/K(+)-ATPase activity in gastric parietal cells, so that TY-11345 should be useful for the clinical treatment of peptic ulcer diseases."

Related Drugs and Biologics

1.	Indomethacin (Indometacin)
2.	Epirizole
3.	Ethanol (Ethyl Alcohol)
4.	Adenosine Triphosphatases (ATPase)