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prohormone thiol protease

catalyzes the final step of (Met)enkephalin sythesis in chromaffin granules

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Hydrolases: 2166
    - Peptide Hydrolases: 23957
      - Cysteine Proteases: 1964
        Cysteine Endopeptidases: 4
        prohormone thiol protease: 1
      - Endopeptidases: 633
        Cysteine Endopeptidases: 4
        prohormone thiol protease: 1

Experts

1.	Burton, D: 1 article (07/2001)
2.	Deftos, L J: 1 article (07/2001)
3.	Hastings, R H: 1 article (07/2001)
4.	Hook, V Y: 1 article (07/2001)
5.	Yasothornsrikul, S: 1 article (07/2001)

Related Diseases

1.

Lung Neoplasms (Lung Cancer)

07/27/2001 - "The coexpression of the prohormone processing enzyme PTP ("prohormone thiol protease") in PTHrP-containing lung cancer cells, and the lack of PTP in cell lines that contain little PTHrP, implicate PTP as a candidate processing enzyme for proPTHrP. "
07/27/2001 - "Proteolysis of ProPTHrP(1-141) by "prohormone thiol protease" at multibasic residues generates PTHrP-related peptides: implications for PTHrP peptide production in lung cancer cells."

Related Drugs and Biologics

1.	Parathyroid Hormone-Related Protein
2.	Peptides (Polypeptides)
3.	Enzymes