capsidiol

isolated from cultured cells of Nicotiana silvestris; structure given in first source

Also Known As:

(1R,3R,4S,4aR,6R)-4,4a-dimethyl-6-prop-1-en-2-yl-2,3,4,5,6,7-hexahydro-1H-naphthalene-1,3-diol; 1,3-Naphthalenediol, 1,2,3,4,4a,5,6,7-octahydro-4,4a-dimethyl-6-(1-methylethenyl)-, (1R,3R,4S,4aR,6R)-

Networked: 6 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Terpenes: 1461
    - Sesquiterpenes: 1370
      - capsidiol: 6

Experts

1.	Song, Kyung-Sik: 1 article (03/2021)
2.	Yang, Eun-Ju: 1 article (03/2021)
3.	Asakura, Nobuhide: 1 article (12/2019)
4.	Hasegawa, Shiori: 1 article (12/2019)
5.	Hirasawa, Taishi: 1 article (12/2019)
6.	Katou, Shinpei: 1 article (12/2019)
7.	Kojima, Tomoya: 1 article (12/2019)
8.	Mizuno, Yuri: 1 article (12/2019)
9.	Takemoto, Daigo: 1 article (12/2019)
10.	Baldwin, Ian T: 1 article (10/2019)

Related Diseases

1.	Infections 08/01/2017 - "However, only a subset of EAS/EAH gene family members were highly induced upon P. infestans infection, which was associated with parallel accumulation of capsidiol in P. infestans-infected pepper. " 10/24/2019 - "An ERF2-like transcription factor regulates production of the defense sesquiterpene capsidiol upon Alternaria alternata infection." 07/01/2019 - "benthamiana leaves substantially increased the numbers of cytoplasmic LDs and supported the accumulation of the sesquiterpenes, 5-epi-aristolochene and capsidiol, up to tenfold over levels elicited by Agrobacterium infection alone. " 08/01/2023 - "hydrophila infection; eleven stress-related metabolite markers were identified, including N-acetylglutamic acid, capsidiol, sedoheptulose 7-phosphate, prostaglandin B1, 8,9-DiHETrE, 12,13-DHOME, ADP, cellobiose, 1H-Indole-3-carboxaldehyde, sinapic acid and 5,7-dihydroxyflavone."
2.	Wounds and Injuries (Trauma) 12/21/2019 - "By inducing transcripts, not the proteins, of EAS and possibly other capsidiol synthesis genes at wound sites, plants can produce large quantities of capsidiol quickly if pathogens invade the wound site, whereas plants can minimize energy loss and avoid the cytotoxic effects of capsidiol where pathogens do not gain entry during wound healing."
3.	Multiple Sclerosis 03/01/2021 - "Capsidiol was examined in cultures of primary splenocytes (SPLCs) isolated from healthy C57BL/6 mice and from those with induced experimental autoimmune encephalomyelitis (EAE) as a mouse model for autoimmune neurodegenerative multiple sclerosis (MS). "
4.	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 03/01/2021 - "Capsidiol was examined in cultures of primary splenocytes (SPLCs) isolated from healthy C57BL/6 mice and from those with induced experimental autoimmune encephalomyelitis (EAE) as a mouse model for autoimmune neurodegenerative multiple sclerosis (MS). "
5.	Neuroinflammatory Diseases 03/01/2021 - "The ameliorative effects of capsidiol isolated from elicited Capsicum annuum on mouse splenocyte immune responses and neuroinflammation."

Related Drugs and Biologics

1.	Sesquiterpenes
2.	Transcription Factors (Transcription Factor)
3.	Proteins (Proteins, Gene)
4.	Cellobiose
5.	Adenosine Diphosphate (ADP)
6.	5-epi-aristolochene
7.	sinapinic acid
8.	chrysin
9.	prostaglandin B1
10.	sedoheptulose 7-phosphate