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modified FAD

differences between mFAD & FAD reside in the 2'-3' carbon atoms of ribityl side chain of riboflavin

Also Known As:

mFAD

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Purines: 651
      - Purine Nucleotides: 140
        Adenine Nucleotides: 1066
        Flavin-Adenine Dinucleotide: 1493
        modified FAD: 1
    - Pteridines: 147
      - Flavins: 50
        Riboflavin: 2218
        Flavin-Adenine Dinucleotide: 1493
        modified FAD: 1
  - 3-Ring Heterocyclic Compounds
    - Flavins: 50
      - Riboflavin: 2218
        Flavin-Adenine Dinucleotide: 1493
        modified FAD: 1
Enzymes and Coenzymes: 1
- Coenzymes: 558
  - Flavins: 50
    - Riboflavin: 2218
      - Flavin-Adenine Dinucleotide: 1493
        modified FAD: 1
Nucleic Acids, Nucleotides, and Nucleosides: 1
- Nucleotides: 15763
  - Ribonucleotides: 307
    - Adenine Nucleotides: 1066
      - Flavin-Adenine Dinucleotide: 1493
        modified FAD: 1
  - Purine Nucleotides: 140
    - Adenine Nucleotides: 1066
      - Flavin-Adenine Dinucleotide: 1493
        modified FAD: 1
Biological Factors: 2472
- Biological Pigments: 1
  - Flavins: 50
    - Riboflavin: 2218
      - Flavin-Adenine Dinucleotide: 1493
        modified FAD: 1

Related Diseases

1.	Colorectal Neoplasms (Colorectal Cancer) 10/01/2023 - "By screening a series of pan-inhibitors, we identified pracinostat, a pan-histone deacetylase (HDAC) inhibitor, as a novel MFAD inducer, that exhibited a significant anticancer effect on colorectal cancer (CRC) in vivo and in vitro. "
2.	Neoplasms (Cancer) 10/01/2023 - "Thus, our results revealed the anticancer mechanism of HDACi pracinostat in CRC via activating CDK5-Drp1 signaling to cause selective MFAD of those CDK5-high tumor cells, which implicates a new paradigm to develop potential therapeutic strategies for CRC treatment."

Related Drugs and Biologics

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2.	Histone Deacetylases (Histone Deacetylase)
3.	SB939 compound