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methionine decarboxylase

from fern Dryopteris filix-mas; pyridoxal 5'-phosphate required for activity; converts methionine to 3-(methylthio)propionaldehyde

Also Known As:

L-methionine decarboxylase

Networked: 7 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Lyases: 637
    - Carbon-Carbon Lyases
      - Carboxy-Lyases: 620
        methionine decarboxylase: 7

Experts

1.	Cui, Xuexian: 1 article (05/2022)
2.	Geng, Wen-Chao: 1 article (05/2022)
3.	Ren, Siying: 1 article (05/2022)
4.	Wang, Hong: 1 article (05/2022)
5.	Wu, Bian: 1 article (05/2022)
6.	Zheng, Zhe: 1 article (05/2022)
7.	Bajaj, Jeevisha: 1 article (01/2021)
8.	Choi, Soo-Young: 1 article (01/2021)
9.	Han, Jaeseok: 1 article (01/2021)
10.	Jun, Nayoung: 1 article (01/2021)

Related Diseases

1.	Neoplasms (Cancer) 05/16/2022 - "Methionine starvation caused by methionine decarboxylase (MetDC) degradation becomes a promising strategy for cancer treatment. " 06/15/2016 - "Polyamine content, which is associated with tumor growth, can be regulated by ornithine decarboxylase (ODC) and S-adenosyl methionine decarboxylase (SAMDC), two key enzymes in polyamine biosynthesis. "
2.	Starvation 05/16/2022 - "Methionine starvation caused by methionine decarboxylase (MetDC) degradation becomes a promising strategy for cancer treatment. "
3.	Prostatic Neoplasms (Prostate Cancer) 03/15/1984 - "This suggests that inhibition of polyamine biosynthetic enzymes, ornithine decarboxylase (ODC) and S-adenosyl-methionine decarboxylase (SAMDC) may retard the growth of prostatic cancer. "
4.	Myeloid Leukemia (Leukemia, Myelocytic) 01/01/2021 - "Polyamines are critical elements in mammals, but it remains unknown whether adenosyl methionine decarboxylase (AMD1), a rate-limiting enzyme in polyamine synthesis, is required for myeloid leukemia. "
5.	Infections 07/01/2005 - "S-adenosyl methionine decarboxylase activity is required for the outcome of herpes simplex virus type 1 infection and represents a new potential therapeutic target." 07/01/2005 - "We show that inhibition of S-adenosyl methionine decarboxylase, a key enzyme of the polyamine metabolic pathway, prevents HSV-1 infection. "

Related Drugs and Biologics

1.	Enzymes
2.	Polyamines
3.	Ornithine Decarboxylase (Decarboxylase, Ornithine)
4.	Methionine (L-Methionine)
5.	Hydroxymethyl and Formyl Transferases
6.	5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase (Methyltetrahydrofolate Homocysteine Methyltransferase)
7.	Serine (L-Serine)
8.	Cystathionine