HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

hippeastrine

isolated from Amaryllidaceae; structure given in first source; RN given refers to (5alpha)-isomer

Also Known As:

hippeastrine hydrobromide, (5alpha)-isomer

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amines: 4871
  - Ethylamines: 5
    - Phenethylamines: 28
      - Amaryllidaceae Alkaloids: 33
        hippeastrine: 3
Heterocyclic Compounds: 198
- Alkaloids: 5398
  - Amaryllidaceae Alkaloids: 33
    - hippeastrine: 3

Experts

1.	Brennand, Kristen J: 1 article (01/2017)
2.	Cederquist, Gustav Y: 1 article (01/2017)
3.	Chen, Shuibing: 1 article (01/2017)
4.	Evans, Todd: 1 article (01/2017)
5.	Fan, Yujie: 1 article (01/2017)
6.	Hartley, Brigham J: 1 article (01/2017)
7.	Mukherjee, Suranjit: 1 article (01/2017)
8.	Schwartz, Robert E: 1 article (01/2017)
9.	Studer, Lorenz: 1 article (01/2017)
10.	Tan, Lei: 1 article (01/2017)

Related Diseases

1.	Neoplasms (Cancer) 12/06/2016 - "Collectively, these results suggested that hippeastrine could be a very promising anticancer candidate for the therapy of cancer in the near future." 01/01/2016 - "One of the AAs, hippeastrine, with the highest EF at 49.3%, was further tested against topoisomerase I, and the IC50 value of hippeastrine was determined to be 23.0 μmol/L, which is comparable with the well-known anti-cancer drug camptothecin at 19.3 μmol/L. "
2.	Zika Virus Infection 01/01/2017 - "We performed a high-content chemical screen using human pluripotent stem cell-derived cortical neural progenitor cells (hNPCs) and found that hippeastrine hydrobromide (HH) and amodiaquine dihydrochloride dihydrate (AQ) can inhibit ZIKV infection in hNPCs. "

Related Drugs and Biologics

1.	Type I DNA Topoisomerases (Topoisomerase I)
2.	Camptothecin
3.	Amodiaquine (Camoquin)

Related Therapies and Procedures

1.	Therapeutics