squamocin
from seeds of Annona squamosa; a trihydroxy-bis-tetrahydrofuran fatty acid lactone; inhibits E. coli NADH:quinone oxidoreductase (NDH-1); structure given in first source
Also Known As:
annonin I; 2(5H)-Furanone, 3-(13-(5'-(1,5-dimethylundecyl)octahydro(2,2'-bifuran)-5-yl)-13-hydroxytridecyl)-5-methyl-
Networked: 12
relevant articles (0 outcomes,
1 trials/studies)
Bio-Agent Context: Research Results
Experts
1. | Wei, Xiao-Yi:
3 articles
(01/2020 - 02/2002)
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2. | Wu, Yang-Chang:
3 articles
(02/2011 - 01/2006)
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3. | Jiang, Zi-Hua:
2 articles
(01/2020 - 01/2014)
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4. | Shi, Jing-Fang:
2 articles
(01/2020 - 01/2014)
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5. | Wu, Ping:
2 articles
(01/2020 - 01/2014)
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6. | Lin, Yi-Hsiung:
2 articles
(02/2011 - 04/2006)
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7. | Cheng, Xiao-Li:
1 article
(01/2020)
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8. | Chen, Jian-Wei:
1 article
(05/2016)
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9. | Chen, Ya-Yun:
1 article
(05/2016)
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10. | Chen, Yong:
1 article
(05/2016)
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Related Diseases
1. | Breast Neoplasms (Breast Cancer)
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2. | Neoplasms (Cancer)
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3. | Leukemia
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4. | BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
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5. | Lung Neoplasms (Lung Cancer)
05/01/2016
- " 10 kinds of annonaceous acetogenins were selected for antitumor activity testing against human lung cancer cell line A549/Taxol and the structure activity relationship was analyzed.MTT assay was used to detect the inhibitory activities of 10 kinds of annonaceous acetogenins and positive drugs against A549/Taxol cells, respectively uvariamicin-Ⅲ(1), uvariamicin-Ⅱ(2), annosquacin D(3), desacetyluvaricin(4), annosquatin A(5), squamostatin D(6), bullatacin(7), squamocin(8), motrilin(9), annosquatin B(10), verapamil and cisplatin. "
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