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saterinone
structure given in first source
Also Known As:
1,2-dihydro-5-(4-(2-hydroxy-3-(4-(2-methoxyphenyl)-1-piperazinyl)propoxy)phenyl)-6-methyl-2-oxo-3-pyridinecarbonitrile; BDF 8634; BDF-8634
Networked:
6
relevant articles (
1
outcomes,
2
trials/studies)
Relationship Network
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Pyridines: 88
Pyridones: 14
saterinone: 6
Piperazines: 26
saterinone: 6
Experts
1.
Baumann, G
: 1 article (10/2003)
2.
Eichner, E
: 1 article (10/2003)
3.
Iven, H
: 1 article (10/2003)
4.
Kieback, A G
: 1 article (10/2003)
5.
Ruckdeschel, W
: 1 article (10/2003)
6.
Stolzenburg, K
: 1 article (10/2003)
Related Diseases
1.
Heart Failure
08/01/1996 - "
Saterinone: A New Dual-Action Drug in the Acute Management of Chronic Heart Failure.
"
10/01/2003 - "
In this study, the pharmacokinetics and hemodynamic effects of the PDE III-inhibitor saterinone were examined in twelve male patients with severe chronic heart failure.
"
05/01/1997 - "
In a double-blind, placebo-controlled design, 36 patients with moderate to severe heart failure were studied (saterinone, n = 24; placebo, n = 12).
"
10/01/2003 - "
Pharmacokinetics and hemodynamic effects of the phosphodiesterase III inhibitor saterinone in patients with chronic heart failure.
"
05/01/1997 - "
These results suggest that intravenous saterinone has a significant vasodilating effect in patients with moderate to severe chronic heart failure (CHF), without exerting an adverse effect on the autonomic nervous system, as demonstrated by assessment of plasma neurohormones and HRV analysis.
"
2.
Dilated Cardiomyopathy (Cardiomyopathy, Congestive)
10/01/1998 - "
The acute hemodynamic effects of the phosphodiesterase (PDE) III inhibitor saterinone were compared with dobutamine and sodium nitroprusside in 12 patients with idiopathic congestive cardiomyopathy (NYHA III).
"
Related Drugs and Biologics
1.
Type 3 Cyclic Nucleotide Phosphodiesterases
2.
adibendan
3.
pimobendan
4.
Milrinone (Primacor)
5.
Neurotransmitter Agents (Neurotransmitter)
6.
Purinergic P1 Receptors (Adenosine Receptor)
7.
Cholinergic Receptors
8.
Phosphoric Diester Hydrolases (Phosphodiesterases)
9.
Nitroprusside (Sodium Nitroprusside)
10.
Dobutamine