ICI 192605

structure given in first source; thromboxane receptor antagonist

Also Known As:

6-(2-(2-chlorophenyl-4-hydroxyphenyl)-1,3-dioxan-5-yl)hexenoic acid; ICI-192605; 4-Hexenoic acid, 6-(2-(2-chlorophenyl)-4-(2-hydroxyphenyl)-1,3-dioxan-5-yl)-, (2alpha,4alpha,5alpha(Z))-

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Dioxanes
    - ICI 192605: 1

Experts

1.	Adams, Gregory: 1 article (01/2016)
2.	Canning, Brendan J: 1 article (01/2016)
3.	Hewitt, Matthew M: 1 article (01/2016)
4.	Mazzone, Stuart B: 1 article (01/2016)
5.	Mori, Nanako: 1 article (01/2016)
6.	Yu, Li: 1 article (01/2016)

Related Diseases

1.	Cough 01/01/2016 - "Bradykinin-evoked cough was potentiated by inhibition of both neutral endopeptidase and angiotensin-converting enzyme (with thiorphan and captopril, respectively), but was largely unaffected by muscarinic or thromboxane receptor blockade (atropine and ICI 192605), cyclooxygenase, or nitric oxide synthase inhibition (meclofenamic acid and N(G)-nitro-L-arginine). "

Related Drugs and Biologics

1.	Nitric Oxide Synthase (NO Synthase)
2.	Cholinergic Agents (Cholinergics)
3.	Thromboxane Receptors (Thromboxane Receptor)
4.	Neprilysin (Neutral Endopeptidase)
5.	Thiorphan
6.	Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)
7.	Meclofenamic Acid (Meclofenamate)
8.	Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)
9.	Captopril (Capoten)
10.	Bradykinin