HOME
PRODUCTS
COMPANY
CONTACT
FAQ
Research
Dictionary
Pharma
Sign Up
FREE
or
Login
Username:
Password:
Remember login
Login
Send password reminder...
rodorubicin
structure given in first source
Also Known As:
cytorhodin S
Networked:
4
relevant articles (
0
outcomes,
1
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Hydrocarbons: 1713
Cyclic Hydrocarbons: 97
Aromatic Hydrocarbons: 291
Polycyclic Aromatic Hydrocarbons: 2020
Naphthacenes
Anthracyclines: 9423
rodorubicin: 4
Polycyclic Compounds: 6
Polycyclic Aromatic Hydrocarbons: 2020
Naphthacenes
Anthracyclines: 9423
rodorubicin: 4
Carbohydrates: 22023
Glycosides: 2119
Aminoglycosides: 5131
Anthracyclines: 9423
rodorubicin: 4
Related Diseases
1.
Neoplasms (Cancer)
04/01/1989 - "
Phase I studies of rodorubicin single bolus and daily times five, once every three weeks in patients with advanced solid tumors.
"
04/01/1988 - "
Rodorubicin might be an interesting new candidate for further clinical evaluation and is the first drug being developed clinically in spite its inactivity in animal transplantation tumor systems.
"
04/01/1988 - "
Rodorubicin is not active in the typical animal transplantation tumors and might therefore be a new leading structure with preferential activity against slow proliferating human tumors.
"
04/01/1988 - "
Rodorubicin is a new tetraglycosidic anthracycline, which was detected because of its activity against human tumors in a human tumor based screening system.
"
2.
Small Cell Lung Carcinoma (Small Cell Lung Cancer)
03/01/1990 - "
Rodorubicin was similarly attached to MoAb BW 575/931/2, directed against a small cell lung cancer associated antigen and to MoAb BW 431/26, recognizing an epitope detectable on carcinoembryonic antigen.
"
3.
Pancreatic Neoplasms (Pancreatic Cancer)
03/01/1990 - "
The corresponding p-maleimidobenzoyl derivatives of beta-rhodomycin I, N,N-dimethyldaunorubicin, and rodorubicin have been attached to thiol groups of the hinge region of reduced monoclonal antibody BW 494/32, directed against a pancreatic cancer associated glycoprotein antigen, resulting in MoAb BW 494/32 conjugates, carrying 4.8-6.8 mol of cytotoxic residues/mol of MoAb.
"
4.
Carcinoma (Carcinomatosis)
01/01/1989 - "
Cytorhodin-S, an anthracycline derivative, was covalently coupled to a monoclonal antibody (mAb) CA208, against carcinoembryonic antigen (CEA) in order to achieve selective killing of a CEA-producing colon carcinoma cell line, COLO 205.
"
Related Drugs and Biologics
1.
Anthracyclines
2.
Carcinoembryonic Antigen
3.
Monoclonal Antibodies
4.
Sulfhydryl Compounds (Thiols)
5.
Glycoproteins (Glycoprotein)
6.
Antigens
7.
Epitopes
8.
N,N-dimethyldaunorubicin
9.
rhodomycin
Related Therapies and Procedures
1.
Transplantation