cysteine proteinase I
cleaves peptides primarily from the C-terminal region of thyroglobulin making thyroid hormone-containing sites accessible to cleavage by other endopeptidases
Also Known As:
Tg hydrolase; thyroglobulin hydrolase
Networked: 2
relevant articles (0 outcomes,
0 trials/studies)
Bio-Agent Context: Research Results
Experts
1. | Friedman, Jacob E:
1 article
(01/2013)
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2. | Heerwagen, Margaret J R:
1 article
(01/2013)
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3. | Janssen, Rachel C:
1 article
(01/2013)
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4. | Stewart, Michael S:
1 article
(01/2013)
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5. | de la Houssaye, Becky A:
1 article
(01/2013)
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6. | Bruce, Clinton R:
1 article
(05/2008)
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7. | Castelli, Laura A:
1 article
(05/2008)
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8. | Hoy, Andrew J:
1 article
(05/2008)
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9. | Kemp, Bruce E:
1 article
(05/2008)
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10. | Kraegen, Edward W:
1 article
(05/2008)
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Related Diseases
1. | Insulin Resistance
01/01/2013
- " E18.5 Fetuses from WT-HFD mothers had larger placentas (P<0.02), as well as increased placenta and fetal liver TG deposition (P<0.01 and P<0.02, respectively) and increased placental LPL TG-hydrolase activity (P<0.02), which correlated with degree of maternal insulin resistance (r = 0.59, P<0.02). " 05/01/2008
- " Although ATGL content and TG hydrolase activity are decreased in obese, insulin-resistant phenotypes, overexpression does not rescue the condition, indicating reduced ATGL is unlikely to be a primary cause of obesity-associated insulin resistance." 05/01/2008
- " When ATGL protein expression and TG hydrolase activity in obese, insulin-resistant rats were restored to levels observed in lean rats, TG content was reduced; however, the insulin resistance induced by the high-fat diet persisted. "
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2. | Obesity
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