hydroxypropylmethylcellulose acetate succinate

structure given in first source

Also Known As:

HPMCAS; hydroxypropyl methylcellulose acetate succinate; hypromellose acetate succinate; Cellulose, 2-hydroxypropyl methyl ether, acetate hydrogen butanedioate

Networked: 7 relevant articles (2 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Carbohydrates: 22023
- Polysaccharides: 15383
  - Glucans: 1624
    - Cellulose: 1972
      - Methylcellulose: 726
        hydroxypropylmethylcellulose acetate succinate: 7

Experts

1.	Benevides, Valdinete Pereira: 1 article (11/2022)
2.	Cabrera, Julia Memrava: 1 article (11/2022)
3.	Chorilli, Marlus: 1 article (11/2022)
4.	Claire, Sunil: 1 article (11/2022)
5.	Ferreira, Taísa Santiago: 1 article (11/2022)
6.	Junior, Angelo Berchieri: 1 article (11/2022)
7.	Meneguin, Andréia Bagliotti: 1 article (11/2022)
8.	Monte, Daniel F M: 1 article (11/2022)
9.	Pavan, Fernando Rogério: 1 article (11/2022)
10.	Rodrigues Alves, Lucas Bocchini: 1 article (11/2022)

Related Diseases

1.	Colorectal Neoplasms (Colorectal Cancer) 05/28/2014 - "To be effective in colorectal cancer prevention and inhibition, the produced microcomposite contained hypromellose acetate succinate, which is insoluble in acidic conditions but highly dissolving at neutral or alkaline pH conditions. "
2.	Tuberculosis (Tuberculoses) 02/15/2018 - "The efficacy of rifapentine, an oral antibiotic used to treat tuberculosis, may be reduced due to degradation at gastric pH and low solubility at intestinal pH. We hypothesized that delivery properties would be improved in vitro by incorporating rifapentine into pH-responsive amorphous solid dispersions (ASDs) with cellulose derivatives including: hydroxypropylmethylcellulose acetate succinate (HPMCAS), cellulose acetate suberate (CASub), and 5-carboxypentyl hydroxypropyl cellulose (CHC). "
3.	Infections 11/01/2022 - "HPMCAS-Coated Alginate Microparticles Loaded with Ctx(Ile21)-Ha as a Promising Antimicrobial Agent against Salmonella Enteritidis in a Chicken Infection Model." 02/01/2023 - "Chitosan and HPMCAS double-coating as protective systems for alginate microparticles loaded with Ctx(Ile21)-Ha antimicrobial peptide to prevent intestinal infections." 11/01/2022 - "The aim of this study was to evaluate the effect of hypromellose acetate/succinate (HPMCAS)-coated alginate microparticles containing the Ctx(Ile21)-Ha antimicrobial peptide (AMP) on both intestinal colonization and systemic infection of laying hens challenged with S. "
4.	Sleep Wake Disorders 02/05/2023 - "By using a combination of placebo and drug loaded compartments comprising of immediate release (hydroxypropyl cellulose) and pH dependant polymers (hypromellose acetate succinate) we were able to customise the release kinetics of melatonin and caffeine that can potentially be used for the treatment of sleep disorders. "
5.	Hepatic Echinococcosis 01/01/2021 - "Improvement of the Bioavailability and Anti-hepatic Alveolar Echinococcosis Effect of Albendazole-Isethionate/Hypromellose Acetate Succinate (HPMC-AS) Complex."

Related Drugs and Biologics

1.	hydroxypropylmethylcellulose acetate succinate
2.	hydroxypropylcellulose (hydroxypropyl cellulose)
3.	Cellulose
4.	Anti-Bacterial Agents (Antibiotics)
5.	rifapentine (Priftin)
6.	acetylcellulose
7.	Alginates
8.	Antimicrobial Peptides
9.	Adenosine Monophosphate (AMP)
10.	Chitosan