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4-(4-guanidinobenzoyloxy)phenylacetic acid

RN given refers to monomethanesulfonate

Also Known As:

FOY 251; FOY-251

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amidines: 14
  - Guanidines: 29
    - 4-(4-guanidinobenzoyloxy)phenylacetic acid: 3

Experts

1.	Bajraktari-Sylejmani, Gzona: 1 article (04/2021)
2.	Haefeli, Walter Emil: 1 article (04/2021)
3.	Weiss, Johanna: 1 article (04/2021)
4.	Arai, Hayato: 1 article (01/2021)
5.	Furukawa, Kenji: 1 article (01/2021)
6.	Haranaka, Miwa: 1 article (01/2021)
7.	Hikima, Tomohiro: 1 article (01/2021)
8.	Iida, Hiroyuki: 1 article (01/2021)
9.	Kitagawa, Junsaku: 1 article (01/2021)
10.	Mukai, Jiro: 1 article (01/2021)

Related Diseases

1.	Infections 01/01/2021 - "Recently, camostat mesylate and its active metabolite 4-(4-guanidinobenzoyloxy)phenylacetic acid (GBPA) were reported to inhibit the infection of cells by severe acute respiratory syndrome coronavirus 2 by inhibiting type II transmembrane serine protease. "
2.	Breast Neoplasms (Breast Cancer) 04/01/2021 - "We therefore tested in vitro the potential inhibition of important efflux (P-glycoprotein (P-gp, ABCB1), breast cancer resistance protein (BCRP, ABCG2)), and uptake transporters (organic anion transporting polypeptides OATP1B1, OATP1B3, OATP2B1) by camostat mesylate and its active metabolite 4-(4-guanidinobenzoyloxy)phenylacetic acid (GBPA). "
3.	Body Weight (Weight, Body) 01/01/2019 - "In ob/ob mice, CS in chow (9-69 mg/kg) or FOY-251 (46 mg/kg) reduced food intake and body weight gain to a similar extent as pair-fed mice. "

Related Drugs and Biologics

1.	camostat
2.	Serine Proteases (Serine Protease)
3.	Organic Anion Transporters
4.	Member 1 Subfamily B ATP Binding Cassette Transporter
5.	Proteins (Proteins, Gene)
6.	Peptides (Polypeptides)