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N- 4- nitrobenzo- 2- oxa- 1,3- diazoleaminocaproyl sphingosylphosphorylcholine

Also Known As:

NBD-sphingomyelin

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Oxazoles: 89
      - Oxadiazoles: 146
        4-Chloro-7-nitrobenzofurazan: 3
        N-4-nitrobenzo-2-oxa-1,3-diazoleaminocaproyl sphingosylphosphorylcholine: 1
Carbohydrates: 22023
- Glycoconjugates: 1353
  - Glycolipids: 2799
    - Glycosphingolipids: 1659
      - Neutral Glycosphingolipids: 101
        Sphingomyelins: 1514
        N-4-nitrobenzo-2-oxa-1,3-diazoleaminocaproyl sphingosylphosphorylcholine: 1
Lipids: 114793
- Glycolipids: 2799
  - Glycosphingolipids: 1659
    - Neutral Glycosphingolipids: 101
      - Sphingomyelins: 1514
        N-4-nitrobenzo-2-oxa-1,3-diazoleaminocaproyl sphingosylphosphorylcholine: 1
- Membrane Lipids: 1591
  - Phospholipids: 11903
    - Sphingomyelins: 1514
      - N-4-nitrobenzo-2-oxa-1,3-diazoleaminocaproyl sphingosylphosphorylcholine: 1
  - Sphingolipids: 3208
    - Glycosphingolipids: 1659
      - Neutral Glycosphingolipids: 101
        Sphingomyelins: 1514
        N-4-nitrobenzo-2-oxa-1,3-diazoleaminocaproyl sphingosylphosphorylcholine: 1

Experts

1.	Kaneko, Masayuki: 1 article (01/2010)
2.	Murayama, Toshihiko: 1 article (01/2010)
3.	Nakamura, Hiroyuki: 1 article (01/2010)
4.	Okuma, Yasunobu: 1 article (01/2010)
5.	Saito, Takeshi: 1 article (01/2010)
6.	Sasaki, Hirotsune: 1 article (01/2010)
7.	Tada, Eiko: 1 article (01/2010)
8.	Toyomura, Kaori: 1 article (01/2010)

Related Diseases

1.

Adenocarcinoma of Lung

01/01/2010 - "Also we found that 1) treatment of NBD-ceramide-labeled cells (human lung adenocarcinoma A549 cells and Chinese hamster ovary cells) with Na(3)VO(4) increased the amount of NBD-C1P formed within 30 min, 2) the treatment increased production of NBD-caproic acid, a counterpart of sphingosine, by ceramidase within 2 h, 3) expression of ceramide kinase enhanced the Na(3)VO(4)-induced formation of NBD-C1P, and tyrosine kinase inhibitors (herbimycin and genistein) decreased the response, 4) the production of NBD-caproic acid in A549 cells was inhibited by genistein, and 5) the responses for 2 h after Na(3)VO(4) treatment were accompanied by a decrease in the production of NBD-sphingomyelin, not a loss of NBD-ceramide. "

Related Drugs and Biologics

1.	Ceramidases
2.	Genistein
3.	Sphingosine
4.	Tyrosine Kinase Inhibitors
5.	ceramide kinase
6.	N- (7- (4- nitrobenzo- 2- oxa- 1,3- diazole))- 6- aminocaproyl sphingosine
7.	hexanoic acid (hexanoate)
8.	herbimycin