HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

trimethylchlorosilane

Also Known As:

chlorotrimethylsilane

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Organosilicon Compounds: 15
  - Trimethylsilyl Compounds
    - trimethylchlorosilane: 1

Related Diseases

1.

Dehydration (Water Stress)

04/17/1998 - "As a model study, conjugate addition of 4-(trimethylsilyl)-3-butynylmagnesium chloride to enone 7 followed by trapping of the enolate with chlorotrimethylsilane gave trimethysilyl enol ether 8. Iodination of 8 with a mixture of NaI and m-CPBA afforded iodo ketone 6. Radical cyclization of 6 effected by Bu(3)SnH and AIBN gave 5. Epoxidation of 5 with m-CPBA yielded epoxy ketone 9. Desilylation and rearrangement of 9 by formic acid gave aldehyde 4. Aldol condensation and dehydration furnished angular triquinane skeleton 3. Total synthesis of (-)-5-oxosilphiperfol-6-ene (1) was accomplished in 12 steps starting from keto ester 14 based on this route. "

Related Drugs and Biologics

1.	Ketones
2.	Ether (Diethyl Ether)
3.	Esters
4.	Chlorides
5.	Aldehydes
6.	3-hydroxybutanal (aldol)
7.	formic acid (formate)
8.	azobis(isobutyronitrile) (AIBN)
9.	3-chloroperbenzoic acid (meta-chloroperoxybenzoic acid)