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1-beta-arabinofuranosylthymine 5'-monophosphate
RN given refers to parent cpd
Also Known As:
1-beta-arabinofuranosylthymine 5'-monophosphate, disodium salt; ara-TMP; arabinofuranosylthymine 5'-monophosphate; thymine arabinonucleoside 5'-phosphate
Networked:
2
relevant articles (
1
outcomes,
0
trials/studies)
Relationship Network
Bio-Agent Context: Research Results
Nucleic Acids, Nucleotides, and Nucleosides: 1
Nucleotides: 15763
Arabinonucleotides: 1
1-beta-arabinofuranosylthymine 5'-monophosphate: 2
Related Diseases
1.
Encephalitis (Encephalitis, Rasmussen)
09/01/1982 - "
When tested against experimental encephalitis in mice inoculated intracerebrally with HSV-1, intraperitoneal or intravenous treatment with 150 mg/kg/day of ara-TMP or 100 mg/kg/day of ara-T, for 5 days was effective in increasing in the mean survival time of mice.
"
2.
Acute Erythroblastic Leukemia (Erythroleukemia)
01/01/1990 - "
Using two murine erythroleukemia cell lines, Friend cell clone F4-6 and F4-12N, the latter being thymidine kinase deficient (TK-) cells transformed to a TK+ phenotype with the HSV TK gene, we have determined 1) the role of cellular and herpes simplex virus thymidine kinase (HSV TK) in the uptake of Ara-T into the cells; 2) the subsequent phosphorylation of intracellular Ara-T to Ara-TMP, Ara-TDP and Ara-TTP; 3) the incorporation of Ara-TTP into the DNA.
"
Related Drugs and Biologics
1.
thymine arabinoside
2.
Thymidine Kinase
3.
DNA (Deoxyribonucleic Acid)
4.
arabinosylthymine 5'-triphosphate