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apolipoprotein SAA
Also Known As:
amyloid-related apoprotein SAA; apo SAA; apoSAA(1); apoSAA(2); apoprotein SAA
Networked:
9
relevant articles (
1
outcomes,
1
trials/studies)
Relationship Network
Bio-Agent Context: Research Results
Lipids: 114793
Lipoproteins: 18361
Apolipoproteins: 14925
apolipoprotein SAA: 9
Amino Acids, Peptides, and Proteins: 1
Proteins: 484843
Lipoproteins: 18361
Apolipoproteins: 14925
apolipoprotein SAA: 9
Apoproteins: 638
Apolipoproteins: 14925
apolipoprotein SAA: 9
Related Diseases
1.
Giant Cell Arteritis (Horton Disease)
03/01/1991 - "
A prospective clinical study of 23 patients with giant-cell arteritis (GCA) and/or polymyalgia rheumatica (PMR) was undertaken in order to assess the behaviour of the non-specific markers of the disease activity, the erythrocyte sedimentation rate (ESR) and other acute phase markers, particularly the C-reactive protein (CPR) and serum amyloid A apolipoprotein (apo SAA) levels during induction of disease remission by prednisone therapy, and possible further recurrence of GCA and/or PMR.
"
2.
Polymyalgia Rheumatica (Rhizomelic Pseudopolyarthritis)
03/01/1991 - "
A prospective clinical study of 23 patients with giant-cell arteritis (GCA) and/or polymyalgia rheumatica (PMR) was undertaken in order to assess the behaviour of the non-specific markers of the disease activity, the erythrocyte sedimentation rate (ESR) and other acute phase markers, particularly the C-reactive protein (CPR) and serum amyloid A apolipoprotein (apo SAA) levels during induction of disease remission by prednisone therapy, and possible further recurrence of GCA and/or PMR.
"
3.
Visceral Leishmaniasis (Kala Azar)
03/01/1992 - "
It was further suggested that the profound changes in the lipoprotein metabolism of these young patients may be due to the increased hepatic synthesis of apolipoprotein SAA and/or to their altered immune function during active visceral Leishmaniasis.
"
03/01/1992 - "
Alterations in lipoprotein density classes in infantile visceral leishmaniasis: presence of apolipoprotein SAA.
"
01/01/1993 - "
The purpose of this study was to determine the effects of antimony treatment on the altered lipoprotein system of four young Tunisians with visceral Leishmaniasis and to further investigate possible relationships between acute phase proteins (C-reactive protein and apolipoprotein SAA)-known to be increased in this disease-and lipid or apolipoprotein (apo) parameters measured before and throughout the treatment.
"
4.
Inflammation (Inflammations)
04/17/1990 - "
The concentration of apo SAA during inflammation is however considerably higher (500-1000-fold) than in controls, which implies a much greater clearance rate during inflammation and involving a process which is apparently not saturable.
"
04/17/1990 - "
Apolipoprotein A-I and apolipoprotein SAA half-lives during acute inflammation and amyloidogenesis.
"
12/01/1987 - "
The apoprotein SAA 2 is the precursor of the amyloid A (AA) fibril protein that is deposited as insoluble fibrils extracellularly in spleen and other organs when amyloidosis occurs secondarily to inflammation.
"
01/01/1990 - "
The measurement of serum amyloid A apolipoprotein (apo SAA) during acute phase inflammation offers a high interest because of its specificity, sensitivity and early increase of its levels, compared to other acute phase proteins.
"
04/17/1990 - "
The half-lives of two apolipoproteins of mouse high-density lipoproteins, apo A-I and apo SAA, were determined in normal animals and compared with those having an inflammatory condition, or inflammation leading to AA amyloid deposition.
"
5.
Amyloidosis
01/01/1990 - "
Apo SAA is the presumed precursor of amyloid A protein, which can be deposited in various tissues, leading to secondary amyloidosis.
"
12/01/1987 - "
The apoprotein SAA 2 is the precursor of the amyloid A (AA) fibril protein that is deposited as insoluble fibrils extracellularly in spleen and other organs when amyloidosis occurs secondarily to inflammation.
"
02/01/1990 - "
In order to determine if AEF played a role in the processing of the apo-SAA protein, three major parameters (apo-SAA1/apo-SAA2 ratios, level of AEF, and fibril formation) were determined during casein-induced secondary amyloidosis.
"
Related Drugs and Biologics
1.
Apolipoproteins
2.
C-Reactive Protein
3.
Serum Amyloid A Protein (Serum Amyloid A)
4.
Prednisone (Sone)
5.
Lipoproteins (Lipoprotein)
6.
Acute-Phase Proteins (Acute-Phase Protein)
7.
Lipids
8.
Antimony
9.
Proteins (Proteins, Gene)
10.
Amyloid (Amyloid Fibrils)
Related Therapies and Procedures
1.
Cardiopulmonary Resuscitation (CPR)
2.
Therapeutics