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tris(chloroethyl)phosphate

has gonadotoxic effects

Also Known As:

Fyrol CEF; Genomoll P; tri(chloroethyl)phosphate; tris(2-chlorethyl)orthophosphate; tris(2-chloroethyl)phosphate

Networked: 3 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Organophosphorus Compounds: 300
  - Organophosphates: 1942
    - tris(chloroethyl)phosphate: 3

Experts

1.	Hale, Robert C: 1 article (01/2017)
2.	La Guardia, Mark J: 1 article (01/2017)
3.	Schreder, Erika D: 1 article (01/2017)
4.	Uding, Nancy: 1 article (01/2017)

Related Diseases

1.	Necrosis 05/01/1993 - "Previous short-term studies of tris(2-chloroethyl)phosphate (TRCP), a flame retardant used in industrial and consumer products, demonstrated that repeated administration of 350 mg TRCP/kg body wt by oral gavage resulted in necrosis of pyramidal neurons in the CA1 region of the hippocampus of F344 rats, but not in B6C3F1 mice. "
2.	Adenoma (Adenomas) 05/01/1991 - "Conclusions: Under the conditions of these 2-year gavage studies, there was clear evidence of carcinogenic activity for male and female F344/N rats receiving tris(2-chloroethyl)phosphate as shown by increased incidences of renal tubule adenomas. "
3.	Hemorrhagic Fever with Renal Syndrome (HFRS) 01/01/2017 - "HFRs detected included those removed from commerce (i.e., polybrominated diphenyl ethers (Penta-BDEs: BDE-47, -85, -100, -99, and -153)), their replacements; e.g., 2-ethylhexyl 2,3,4,5-tetrabromobenzoate (TBB or EH-TBB); bis(2-ethylhexyl) 3,4,5,6-tetrabromophthalate (TBPH or BEH-TEBP) and long-produced chlorinated organophosphate-FRs (ClOPFRs): tris(2-chloroethyl)phosphate (TCEP), tris(1-chloro-2-propyl)phosphate (TCPP or TCIPP), and tris(1,3-dichloro-2-propyl)phosphate (TDCPP or TDCIPP). "

Related Drugs and Biologics

1.	Flame Retardants (Fire Retardants)
2.	Halogenated Diphenyl Ethers
3.	Organophosphates
4.	2-ethylhexyl 2,3,4,5-tetrabromobenzoate
5.	tris(2-carboxyethyl)phosphine
6.	tri-(2-chloroisopropyl)phosphate
7.	PENTA
8.	tetracarboxyphenylporphine
9.	tris(1,3-dichloro-2-propyl)phosphate
10.	tris(1,3-dichloroisopropyl) phosphate