consists of 3 separate proteins: PA (protective antigen/factor), EF (edema factor) & LF (lethal factor); these three are nontoxic proteins that associate in binary or ternary combinations to form toxic complexes at the surface of mammalian cells; Bacillus anthracis calmodulin-dependent adenylate cyclase is component of EF protein, is a zinc-dependent metalloprotease; PA63 is a proteolytic fragment of PA83
Also Known As:
anthrax lethal factor; 63 kDa anthrax protective antigen, Bacillus anthracis; 83 kDa anthrax protective antigen, Bacillus anthracis; Bacillus anthracis calmodulin-dependent adenylate cyclase; Bacillus anthracis, protective antigen; LF protein, Bacillus anthracis; LeTx toxin, B anthracis; PA antigen, Bacillus anthracis; PA63 protective antigen, Bacillus anthracis; PA63 protein, Bacillus anthracis; PA83 protective antigen, Bacillus anthracis; anthrax edema factor; anthrax protective antigen; anthrax toxin EF; anthrax toxin LF; anthrax toxin PA; anthrax toxins translocating protein, Bacillus anthracis; cya protein, Bacillus anthracis; edema factor exotoxin; edema factor, Bacillus anthracis; edema factor, anthrax toxin; edema toxin, Bacillus anthracis; lef protein, Bacillus anthracis; lethal factor, anthrax; lethal toxin, Bacillus anthracis; pag protein, Bacillus anthracis; pagA protein, Bacillus anthracis; protective antigen, anthrax