dan-shen root extract

contains methylenetanshinquinone & 1,2-dihydrotanshinquinone; Chinese drug isolated from Salvia miltiorrhiza; structure given in first source

Also Known As:

1,2-DT-quinone; 1,2-dihydrotanshinquinone; Danshen extract; Salvia miltiorrhiza root; danshen root extract; methylenetanshinquinone; tanshinquinone, methylene-

Networked: 25 relevant articles (3 outcomes, 10 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Zhang, Qian: 2 articles (01/2020 - 09/2019)
2.	Cai, Jin: 1 article (01/2022)
3.	Chen, Weikang: 1 article (01/2022)
4.	Han, Fangxuan: 1 article (01/2022)
5.	Huang, Guolei: 1 article (01/2022)
6.	Ji, Xiaozhen: 1 article (01/2022)
7.	Wang, Bin: 1 article (01/2022)
8.	Ye, Qing-Mei: 1 article (01/2022)
9.	Yu, Miao: 1 article (01/2022)
10.	Zeng, Weinv: 1 article (01/2022)

Related Diseases

1.	Cardiovascular Diseases (Cardiovascular Disease) 12/20/2017 - "This study will provide evidence that Danshen extract is beneficial for stable angina and may establish a possible mechanism of Danshen treatment effects on cardiovascular disease. " 02/01/2019 - "Salvia miltiorrhiza root has been used in Asian traditional medicine for the treatment of cardiovascular diseases, asthma, and other conditions. " 06/01/2009 - "Danshensu (3-(3,4-dihydroxyphenyl) lactic acid), a natural phenolic acid, is isolated from Salvia miltiorrhiza root, and is the most widely used traditional Chinese medicine for the treatment of various cardiovascular diseases. " 01/01/2008 - "Danshensu (3-(3,4-dihydroxyphenyl) lactic acid) and salvianolic acid B, two natural phenolic acids of caffeic acid derivatives isolated from Salvia miltiorrhiza root of the most widely used traditional Chinese medicine for the treatment of various cardiovascular diseases, have been reported to have potential protective effects from oxidative injury. "
2.	Myocardial Infarction 01/28/2020 - "SalB is a major component of the Salvia miltiorrhiza root and has been shown to be an effective treatment for subarachnoid hemorrhages and myocardial infarctions. " 01/01/2020 - "In our study, the employment of a water extracted and alcohol precipitated of danshen extract attenuated cardiac dysfunction and inflammation response in acute myocardial infarction-induced HF rats. "
3.	Stable Angina 12/20/2017 - "This study will provide evidence that Danshen extract is beneficial for stable angina and may establish a possible mechanism of Danshen treatment effects on cardiovascular disease. " 12/20/2017 - "In this study, we aim to investigate the effect of Danshen extract on Lp-PLA2 level in patients with stable angina. " 12/20/2017 - "The effect of Danshen extract on lipoprotein-associated phospholipase A2 levels in patients with stable angina pectoris: study protocol for a randomized controlled trial - the DOLPHIN study."
4.	Subarachnoid Hemorrhage (Aneurysmal Subarachnoid Hemorrhage) 01/28/2020 - "SalB is a major component of the Salvia miltiorrhiza root and has been shown to be an effective treatment for subarachnoid hemorrhages and myocardial infarctions. "
5.	Reperfusion Injury 11/15/2023 - "Porcine cardiac blood - Salvia miltiorrhiza root alleviates cerebral ischemia reperfusion injury by inhibiting oxidative stress induced apoptosis through PI3K/AKT/Bcl-2/Bax signaling pathway." 06/01/1997 - "I type underwent regional vascular occlusion at hepatic hilus as hepatectomy, and infusion of Danshen extract solution before vascular occlusion to prevent hepatocytes from reperfusion injury. " 07/01/2009 - "The aim of the present study was to evaluate the protective effect of cryptotanshinone (CTS), one of active ingredients of Salvia miltiorrhiza root, on myocardial ischemia-reperfusion injury in rat due to inhibition of some inflammatory events that occur by NF-kappaB-activation during ischemia and reperfusion. "

Related Drugs and Biologics

1.	3,4-dihydroxyphenyllactic acid
2.	Acids
3.	salvianolic acid B
4.	caffeic acid
5.	tanshinone
6.	Proteins (Proteins, Gene)
7.	1-Alkyl-2-acetylglycerophosphocholine Esterase (PAF Acetylhydrolase)
8.	Neuroprotective Agents
9.	NF-kappa B (NF-kB)
10.	Estrogen Receptors

Related Therapies and Procedures

1.	Chinese Traditional Medicine (Traditional Chinese Medicine)
2.	Traditional Medicine (Folk Remedies)
3.	Hepatectomy