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mepregenol diacetate
tested for use in combination with ethinyl estradiol; RN given refers to (3beta)-isomer
Also Known As:
6-methylpregna-4,6-dien-3 beta,17 alpha-diol-20-one diacetate; acetomepregenol
Networked:
3
relevant articles (
1
outcomes,
1
trials/studies)
Relationship Network
Bio-Agent Context: Research Results
Polycyclic Compounds: 6
Fused-Ring Compounds
Steroids: 70059
Pregnanes: 9
Pregnadienes
Pregnadienediols
mepregenol diacetate: 3
Related Diseases
1.
Habitual Abortion (Recurrent Miscarriage)
06/01/1989 - "
Monitoring for pregnancy development and treatment efficacy in 104 females treated with acetomepregenol for threatened recurrent abortion at 8 to 16 week of gestation was performed with the use of ultrasonic variations.
"
06/01/1989 - "
Therapeutic efficacy of acetomepregenol (synthetic progestogen) was evaluated in 104 women (average age was 28.3 years) with threatened habitual abortion at 7-16 weeks of gestation.
"
2.
Spontaneous Abortion (Miscarriage)
06/01/1989 - "
[Acetomepregenol in the treatment of threatened late miscarriages (clinico-experimental study)].
"
06/01/1989 - "
[Use of acetomepregenol in the treatment of threatened habitual miscarriage].
"
06/01/1989 - "
Of 104 women treated with acetomepregenol during the 1st trimester, 87 gave birth to normal babies, 8 had miscarriage at 12-27 weeks of gestation, and 9 had premature labor.
"
3.
Pain (Aches)
06/01/1989 - "
Acetomepregenol was given not earlier than 7-8 weeks of gestation in a daily dose of 0.5-1.5 mg. Total dose per course was 10-45 mg; daily dose was gradually tapered off to 0.26-0.125 mg. During the treatment, 77.9% of the patients showed alleviation or complete disappearance of pain (on day 2-4), 87.5% showed normalization of urinary chorionic gonadotropin levels (1.5-2 weeks after the onset of treatment), and 88.6% showed normalization of the basal temperature (on day 5-7).
"
4.
Neoplasms (Cancer)
01/01/1997 - "
Antitumor effect on hormone dependent tumors has been demonstrated following oral and parenteral treatment of mice and rats with a gestagenic drug -- acetomepregenol.
"
5.
Nausea
06/01/1989 - "
The only side-effect of acetomepregenol was nausea recorded in 24% of the patients.
"
Related Drugs and Biologics
1.
Progestins (Progestagens)
2.
Hormones (Hormone)
3.
Chorionic Gonadotropin (Human Chorionic Gonadotropin)