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methoxysuccinyl- alanyl- alanyl- prolyl- valine chloromethyl ketone
prevents elastase-induced emphysema
Also Known As:
MSAAPVCK; MeOSuc-AAPV-CMK; methoxy-Suc-Ala-Ala-Pro-Val-chloromethyl ketone
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Amino Acids, Peptides, and Proteins: 1
Amino Acids: 30675
Amino Acid Chloromethyl Ketones
methoxysuccinyl-alanyl-alanyl-prolyl-valine chloromethyl ketone: 1
Related Diseases
1.
Hemorrhage
03/01/1990 - "
Methoxysuccinyl-alanyl-alanyl-prolyl-valine-chloromethylketone (MeOSuc-AAPV-CMK), as well as alpha 1-proteinase inhibitor (alpha 1PI) but not tosyl-lysine-chloromethylketone (tosyl-lysine-CMK), inhibited the hemorrhage caused by human PMN elastase, but the specific inhibitors of this enzyme had no effect on thermolysin-induced lung hemorrhage.
"
Related Drugs and Biologics
1.
Leukocyte Elastase (Neutrophil Elastase)
2.
Thermolysin
3.
Lysine (L-Lysine)
4.
Enzymes
5.
alpha 1-Antitrypsin (alpha 1 Antitrypsin)
6.
alanyl-alanyl-prolyl-valine