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N-acetylamrinone
structure given in first source
Also Known As:
N-(1,6-dihydro-5-oxo(3,4'-bipyridin)-5-yl)acetamide; Acetamide, N-(1,6-dihydro-6-oxo(3,4'-bipyridin)-5-yl)-
Networked:
2
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Amines: 4871
Aminopyridines: 77
Amrinone: 346
N-acetylamrinone: 2
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Pyridines: 88
Aminopyridines: 77
Amrinone: 346
N-acetylamrinone: 2
Related Diseases
1.
Sepsis (Septicemia)
09/01/1996 - "
Hemodynamic effects of N-acetylamrinone in a porcine model of group B streptococcal sepsis.
"
09/01/1996 - "
We conclude that amrinone, but not N-acetylamrinone, causes pulmonary vasodilation in a porcine model of sepsis and that the parent drug is the sole active component in amrinone.
"
2.
Thrombocytopenia (Thrombopenia)
06/01/1993 - "
This association suggests that N-acetylamrinone, and not amrinone, may be the mediator of thrombocytopenia in children receiving amrinone.
"
06/01/1993 - "
N-Acetylamrinone peak concentration, steady-state concentration, N-acetylamrinone AUC, and ratio of N-acetylamrinone to amrinone were greater in patients with thrombocytopenia.
"
06/01/1993 - "
Eighteen children receiving amrinone after heart surgery were prospectively evaluated to correlate the pharmacokinetics of amrinone and N-acetylamrinone with thrombocytopenia.
"
Related Drugs and Biologics
1.
Amrinone (Amrinon)