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proxyl nitroxide

structure

Also Known As:

2,2,5,5-tetramethylpyrrolidine-N-oxyl nitroxide; 1-Pyrrolidinyloxy, 2,2,5,5-tetramethyl-

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Heterocyclic Oxides
  - Cyclic N-Oxides: 3
    - proxyl nitroxide: 3

Experts

1.	Kalyanaraman, Balaraman: 2 articles (01/2018 - 01/2017)
2.	Boyle, Kathleen A: 1 article (01/2018)
3.	Dwinell, Michael B: 1 article (01/2018)
4.	Hill, R Blake: 1 article (01/2018)
5.	Marchese, Adriano: 1 article (01/2018)
6.	Van Wickle, Jonathan: 1 article (01/2018)
7.	Dhanasekaran, Anuradha: 1 article (01/2017)
8.	Pant, Tarun: 1 article (01/2017)
9.	Ravichandran, Abinaya: 1 article (01/2017)
10.	Singh, Apoorva: 1 article (01/2017)

Related Diseases

1.	Mitochondrial Diseases (Mitochondrial Disease) 04/16/2008 - "In particular, low concentrations (approximately 10 nm) of two mitochondrial-targeted antioxidants, ubiquinone and carboxy-proxyl nitroxide, each covalently coupled to a triphenylphosphonium cation (Mito-Q and Mito-CP, respectively), prevented mitochondrial dysfunction, reduced superoxide production in SOD1(G93A) astrocytes, and restored motor neuron survival. "
2.	Colonic Neoplasms (Colon Cancer) 01/01/2018 - "3-Carboxyl proxyl nitroxide (Mito-CP) and Mito-Metformin, two mitochondria-targeted compounds, depleted intracellular ATP levels and persistently inhibited ATP-linked oxygen consumption in both KRAS WT and KRAS variant-containing colon cancer cells and had only limited effects on nontransformed intestinal epithelial cells. "
3.	Burkitt Lymphoma (Burkitt's Lymphoma) 01/01/2017 - "Hence, we studied the effects of mitochondrially targeted carboxy proxyl nitroxide (Mito-CP) and a control ten carbon TPP moiety (Dec-TPP+) in the human Burkitt lymphoma cell line (Daudi) and normal peripheral blood mononuclear cells under hypoxia and normoxia. "
4.	Hypoxia (Hypoxemia) 01/01/2017 - "Hence, we studied the effects of mitochondrially targeted carboxy proxyl nitroxide (Mito-CP) and a control ten carbon TPP moiety (Dec-TPP+) in the human Burkitt lymphoma cell line (Daudi) and normal peripheral blood mononuclear cells under hypoxia and normoxia. "

Related Drugs and Biologics

1.	mito-carboxy proxyl
2.	Ubiquinone
3.	Superoxides (Superoxide)
4.	Metformin (Glucophage)
5.	Cations
6.	Carbon
7.	Antioxidants
8.	Adenosine Triphosphate (ATP)
9.	mitoquinone
10.	triphenylphosphonium