HOME
PRODUCTS
COMPANY
CONTACT
FAQ
Research
Dictionary
Pharma
Sign Up
FREE
or
Login
Username:
Password:
Remember login
Login
Send password reminder...
3-hydroxynorvaline
RN given refers to cpd without isomeric designation; structure
Also Known As:
3-hydroxynorvaline, threo-(DL)-isomer; alpha-amino beta-hydroxyvaleric acid; beta-hydroxynorvaline
Networked:
3
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Amino Acids, Peptides, and Proteins: 1
Amino Acids: 30675
Essential Amino Acids: 1152
Threonine: 2168
3-hydroxynorvaline: 3
Neutral Amino Acids: 200
Threonine: 2168
3-hydroxynorvaline: 3
Related Diseases
1.
Neoplasms (Cancer)
09/10/1980 - "
The importance of threonine in the Asn-X-Thr recognition sequence for asparagine-linked glycosylation was tested by examining the effect of a threonine analog, beta-hydroxynorvaline, on co-translational glycosylation in Krebs' II ascites tumor lysates.
"
2.
Lymphoma (Lymphomas)
05/15/1985 - "
The requirement for intact carbohydrates of glycoproteins at the cell surface was investigated after treatment of lymphoma cells with compounds which interfere at different steps in N-linked glycosylation: swainsonine and 1-deoxynojirimycin act at different levels during the processing, so that complex oligosaccharides cannot be formed; 2-deoxyglucose, beta-hydroxynorvaline, and tunicamycin completely prevent the formation of N-linked (high-mannose as well as complex) oligosaccharides.
"
3.
Infections
10/19/1987 - "
Treatment of HSV-infected cells with 5-10 mM beta-hydroxynorvaline (Hnv), a threonine analog, specifically affects herpesvirus DNA replication: both the rate of and total DNA synthesis are reduced, the former approximately 15-fold by Hnv (6 h post-infection) and the latter by 12-fold (between 3 and 12 h post-infection).
"
4.
Ascites
09/10/1980 - "
The importance of threonine in the Asn-X-Thr recognition sequence for asparagine-linked glycosylation was tested by examining the effect of a threonine analog, beta-hydroxynorvaline, on co-translational glycosylation in Krebs' II ascites tumor lysates.
"
Related Drugs and Biologics
1.
Threonine (L-Threonine)
2.
1-Deoxynojirimycin (1 Deoxynojirimycin)
3.
Swainsonine
4.
Tunicamycin
5.
Oligosaccharides
6.
Mannose (D-Mannose)
7.
Glycoproteins (Glycoprotein)
8.
DNA (Deoxyribonucleic Acid)
9.
Deoxyglucose (2 Deoxy D glucose)
10.
Carbohydrates
Related Therapies and Procedures
1.
Aftercare (After-Treatment)