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JZP327A
A potent human FAAH inhibitor.
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Azoles: 2138
Oxazoles: 89
Oxadiazoles: 146
JZP327A: 1
Related Diseases
1.
Migraine Disorders (Migraine)
06/14/2023 - "
Activity of FAAH-Inhibitor JZP327A in an Experimental Rat Model of Migraine.
"
06/14/2023 - "
Here, we profile the pharmacological activity of the FAAH inhibitor JZP327A, a chiral 1,3,4-oxadiazol-2(3H)-one compound, in the mediation of spontaneous and nocifensive behaviour in the animal models of migraine based on nitroglycerin (NTG) administration.
"
2.
Hyperalgesia
06/14/2023 - "
The findings show that JZP327A did not affect NTG-induced changes in the spontaneous behaviour of rats, while it inhibited NTG-induced hyperalgesia at the orofacial formalin test.
"
Related Drugs and Biologics
1.
Nitroglycerin (Dynamite)
2.
Formaldehyde (Formol)
3.
1,3,4-oxadiazol-2(3H)-one