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11-Cl-BBQ
Also Known As:
11-chloro-7H-benzimidazo(2,1-a)benzo(de)iso-quinolin-7-one
Networked:
2
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
Fused-Ring Heterocyclic Compounds
2-Ring Heterocyclic Compounds
Benzimidazoles: 245
11-Cl-BBQ: 2
Quinolines: 146
Quinolones: 2938
11-Cl-BBQ: 2
Related Diseases
1.
Neoplasms (Cancer)
01/01/2023 - "
11-Cl-BBQ induced AhR-dependent cancer cell-selective growth inhibition and strongly inhibited colony formation in TNBC cells.
"
2.
Lung Neoplasms (Lung Cancer)
01/01/2023 - "
Our results identify 11-Cl-BBQ as a potential lung cancer therapeutic, highlight the feasibility of targeting AhR and provide important mechanistic insights into AhR-mediated-anticancer actions.
"
01/01/2023 - "
Treatment of lung cancer cells with 11-Cl-BBQ induced potent and sustained AhR-dependent anti-proliferative effects by promoting G1 phase cell cycle arrest.
"
01/01/2023 - "
11-Cl-BBQ, a select modulator of AhR-regulated transcription, suppresses lung cancer cell growth via activation of p53 and p27Kip1.
"