monomethoxy poly(ethylene glycol)-b-poly(caprolactone)

01/01/2021 - "Therefore, the mPEG-b-PCL-DOX NPs had a potential application in anti-cancer therapy."
12/01/2019 - "The purpose of this paper was to fabricate a novel methoxy poly(ethylene glycol)-block-poly(caprolactone)-block-poly(1, 4, 8-Trioxa [4.6] spiro-9-undecanone) (mPEG-b-PCL-b-PTOSUO, mPECT) triblock copolymer and study on the in vitro anti-tumor activity of curcumin-loaded mPECT nanoparticles (NPs). "
12/05/2022 - "This prodrug was further loaded into biodegradable monomethoxy poly(ethylene glycol)-b-poly(caprolactone) (mPEG-b-PCL) to improve its solubility and tumor accumulation. "
10/01/2014 - "After Michael-addition reactions between amine groups of cystamine and carbon-carbon double bonds of PPEMA segments, the crosslinked reduction-sensitive copolymer mPEG-b-PCL-b-PPEMA-SS- was obtained for efficient delivery and controlled release of doxorubicin (DOX) to cancer cells. "
06/10/2022 - "In this study, micelles composed of methoxy poly(ethylene glycol)-block-poly(ε-caprolactone) copolymer (mPEG-b-PCL), which has ionically conjugated lithocholic acid (LCA) and providing pH sensitive release of LCA in acidic media, were prepared as drug carrier devices for cancer therapy. "

06/10/2022 - "The novelty of this study is the prepared micelles, which have ionic conjugation of LCA to mPEG-b-PCL, and pH responsive release of LCA demonstrating effective apoptosis on breast cancer cells. "
06/10/2022 - "Lithocholic acid conjugated mPEG-b-PCL micelles for pH responsive delivery to breast cancer cells."
01/01/2016 - "Finally, in vitro assays demonstrated that PTX-loaded TPGS- b-PCL exhibited a significant higher antitumor activity than PTX-loaded mPEG-b-PCL NPs and Abraxane® against an estrogen-dependent (MCF-7) and an estrogen independent (MDA-MB-231) breast cancer cells lines. "
03/01/2015 - "mPEG-b-PCL/TPGS mixed micelles for delivery of resveratrol in overcoming resistant breast cancer."

01/01/2015 - "All the results suggested that the PTX-loaded MPEG-b-PCL NPs that had their surfaces modified with PDA are promising nanocarriers for malignant melanoma therapy. "
01/01/2015 - "Surface modification of MPEG-b-PCL-based nanoparticles via oxidative self-polymerization of dopamine for malignant melanoma therapy."
01/01/2015 - "To enhance the therapeutic effects of chemotherapy on malignant melanoma, paclitaxel (PTX)-loaded methoxy poly(ethylene glycol)-b-poly(ε-caprolactone) nanoparticles (MPEG-b-PCL NPs) that had their surfaces modified with polydopamine (PTX-loaded MPEG-b-PCL NPs@PDA) were prepared as drug vehicles. "