(11R,13S,17S)- 11- (1,3- benzodioxol- 5- yl)- 17- hydroxy- 13- methyl- 17- prop- 1- ynyl- 1,2,6,7,8,11,12,14,15,16- decahydrocyclopenta(a)phenanthren- 3- one

Also Known As:

PT150

Networked: 3 relevant articles (1 outcomes, 0 trials/studies)

1.	Shock 09/01/2021 - "The glucocorticoid antagonist PT150 reduces shock-induced fentanyl seeking, suggesting it may be effective against stress-induced relapse, although the sex difference in response may need further exploration."
2.	Lung Injury 01/01/2022 - "We postulated that the GR and AR modulator, PT150, would reduce infectivity of SARS-CoV-2 and prevent inflammatory lung injury in the Syrian golden hamster model of COVID-19 by down-regulating expression of critical genes regulated through these receptors. "
3.	Substance-Related Disorders (Drug Abuse) 01/01/2018 - "Therefore, future research is needed to validate the use of PT150 in reducing behaviors associated with drug addiction. "
4.	COVID-19 01/01/2022 - "PT150 is therefore a strong candidate for further clinical development for the treatment of COVID-19 across variants of SARS-CoV-2." 01/01/2022 - "We postulated that the GR and AR modulator, PT150, would reduce infectivity of SARS-CoV-2 and prevent inflammatory lung injury in the Syrian golden hamster model of COVID-19 by down-regulating expression of critical genes regulated through these receptors. "