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LPM4870108

Also Known As:

(7S)-10-fluorospiro(5,14-dioxa-2,12,17,21,22,25-hexazapentacyclo(17.5.2.02,7.08,13.022,26)hexacosa-1(25),8(13),9,11,19(26),20,23-heptaene-16,1'-cyclopropane)-18-one

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 4 or More Rings Heterocyclic Compounds
    - LPM4870108: 2

Experts

1.	Duan, Sijin: 2 articles (01/2022 - 06/2021)
2.	Gao, Yonglin: 2 articles (01/2022 - 06/2021)
3.	Li, Chunmei: 2 articles (01/2022 - 06/2021)
4.	Tian, Jingwei: 2 articles (01/2022 - 06/2021)
5.	Wang, Hongbo: 2 articles (01/2022 - 06/2021)
6.	Ji, Shengmin: 1 article (01/2022)
7.	Mao, Yutong: 1 article (01/2022)
8.	Meng, Ping: 1 article (01/2022)
9.	Xu, Yangyang: 1 article (01/2022)
10.	Dong, Lin: 1 article (06/2021)

Related Diseases

1.	Body Weight (Weight, Body) 06/01/2021 - "No evidence of LPM4870108 toxicity was observed over this study as reflected by an absence of difference in body weight, ophthalmoscopy, urinalysis, gross, or histopathology findings. "
2.	Neoplasms (Cancer) 01/01/2022 - "We hypothesized that LPM4870108, an effective anti-cancer Trk inhibitor, might affect the learning and memory via epigenetic modifications. "
3.	Memory Disorders (Memory Loss) 01/01/2022 - "Overall, these data suggest that gene-specific alterations in patterns of DNA methylation can potentially contribute to the incidence of learning and memory deficits associated with exposure to LPM4870108."