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crinecerfont

Also Known As:

4-(2-chloro-4-methoxy-5-methylphenyl)-N-((1S)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl)-5-methyl-N-prop-2-ynyl-1,3-thiazol-2-amine; NBI 74788; NBI-74788

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amines: 4871
  - crinecerfont: 2
- Sulfur Compounds: 278
  - Thiazoles: 392
    - crinecerfont: 2
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Thiazoles: 392
      - crinecerfont: 2

Experts

1.	Auchus, Richard J: 1 article (01/2022)
2.	Chan, Jean L: 1 article (01/2022)
3.	Davis, Shanlee M: 1 article (01/2022)
4.	Farber, Robert H: 1 article (01/2022)
5.	Fechner, Patricia Y: 1 article (01/2022)
6.	Giri, Nagdeep: 1 article (01/2022)
7.	Imel, Erik A: 1 article (01/2022)
8.	Roberts, Eiry: 1 article (01/2022)
9.	Sarafoglou, Kyriakie: 1 article (01/2022)
10.	Sturgeon, Julia: 1 article (01/2022)

Related Diseases

1.	Congenital Adrenal Hyperplasia (Hyperplasia, Congenital Adrenal) 01/01/2022 - "Crinecerfont Lowers Elevated Hormone Markers in Adults With 21-Hydroxylase Deficiency Congenital Adrenal Hyperplasia." 10/18/2023 - "Crinecerfont, a CRF1 Receptor Antagonist, Lowers Adrenal Androgens in Adolescents With Congenital Adrenal Hyperplasia." 10/18/2023 - "Crinecerfont, a corticotropin-releasing factor type 1 receptor antagonist, has been shown to reduce elevated adrenal androgens and precursors in adults with congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency (21OHD), a rare autosomal recessive disorder characterized by cortisol deficiency and androgen excess due to elevated adrenocorticotropin. "
2.	Congenital adrenal hyperplasia due to 21 hydroxylase deficiency 01/01/2022 - "Crinecerfont Lowers Elevated Hormone Markers in Adults With 21-Hydroxylase Deficiency Congenital Adrenal Hyperplasia." 10/18/2023 - "Crinecerfont, a corticotropin-releasing factor type 1 receptor antagonist, has been shown to reduce elevated adrenal androgens and precursors in adults with congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency (21OHD), a rare autosomal recessive disorder characterized by cortisol deficiency and androgen excess due to elevated adrenocorticotropin. "

Related Drugs and Biologics

1.	Hydrocortisone (Cortisol)
2.	Hormones (Hormone)
3.	Corticotropin-Releasing Hormone
4.	Androgens
5.	Adrenocorticotropic Hormone (ACTH)
6.	CRF receptor type 1