3,6-di-O-acetyl-2-deoxy-D-glucopyranose
Also Known As:
((2R,3S,4R)-4-acetyloxy-3,6-dihydroxyoxan-2-yl)methyl acetate; 3,6-di-O-acetyl-2-deoxy-D-glucose; WP-1122; WP1122
Networked: 1
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Bio-Agent Context: Research Results
Experts
Related Diseases
1. | Glioma (Gliomas)
10/01/2019
- " After treatment with WP1122, a decrease in lactate was observed in mice with glioma (baseline and treatment mean kPL, 0.027 and 0.018 sec-1, respectively, P = .01; baseline and posttreatment mean nLac, 0.28 and 0.22, respectively, P = .01) whereas no significant decrease was observed in healthy control mice (baseline and posttreatment mean kPL, 0.011 and 0.017 sec-1, respectively, P = .91; baseline and posttreatment mean nLac, 0.16 and 0.21, respectively, P = .84).ConclusionHyperpolarized carbon 13 measurements of pyruvate metabolism can provide rapid feedback for monitoring treatment response in glioma.© RSNA, 2019."
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