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ZCL-082

Also Known As:

7-(2'-(phenylcarbamoyl)ethyl)-1,3-dihydro-1-hydroxy-2,1-benzoxaborole

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Cai, Haiyan: 1 article (01/2022)
2.	Cao, Yang: 1 article (01/2022)
3.	Ji, Yanjie: 1 article (01/2022)
4.	Lei, Hu: 1 article (01/2022)
5.	Liu, Chuanxu: 1 article (01/2022)
6.	Liu, Ligen: 1 article (01/2022)
7.	Liu, Meng: 1 article (01/2022)
8.	Ma, Chunmin: 1 article (01/2022)
9.	Shan, Huizhuang: 1 article (01/2022)
10.	Wu, Yingli: 1 article (01/2022)

Related Diseases

1.	Ovarian Neoplasms (Ovarian Cancer) 01/05/2022 - "We investigated the effect of ZCL-082, a novel boron-containing compound with anti-proliferating activity against ovarian cancer cells, on NHL cells and human peripheral blood mononuclear cells by CCK-8 assay, Annexin V/PI double staining assay, RH123/PI double staining, Western blot, and immunohistochemistry. "
2.	Non-Hodgkin Lymphoma (Lymphosarcoma) 01/05/2022 - "ZCL-082, a boron-containing compound, induces apoptosis of non-Hodgkin's lymphoma via targeting p90 ribosomal S6 kinase 1/NF-κB signaling pathway."
3.	Lymphoma (Lymphomas) 01/05/2022 - "The combination of ZCL-082 with BCL-2 inhibitor may represent a novel strategy to improve the outcome of double-hit or double-expressor lymphoma." 01/05/2022 - "We found that ZCL-082 is a highly promising anti-lymphoma compound that targets RSK1 and interferes with the RSK1/NF-κB signaling pathway. " 01/05/2022 - "Furthermore, the combination of ZCL-082 and BCL-2 inhibitor ABT-199 has a synergistic apoptosis-inducing effect against double-hit lymphoma cell line OCI-Ly10. "

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