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TAK-041

Also Known As:

2-(4-oxo-1,2,3-benzotriazin-3-yl)-N-((1S)-1-(4-(trifluoromethoxy)phenyl)ethyl)acetamide; TAK041

Networked: 2 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amides: 2428
  - Acetamides: 21
    - TAK-041: 2
- Carboxylic Acids: 973
  - Acyclic Acids
    - Acetates: 4994
      - Acetamides: 21
        TAK-041: 2
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Triazines: 306
    - TAK-041: 2

Experts

1.	Arkilo, Dimitrios: 1 article (01/2022)
2.	Baader-Pagler, Tamara: 1 article (01/2022)
3.	Behrje, Rhett: 1 article (01/2022)
4.	Bretschneider, Tom: 1 article (01/2022)
5.	Deiana, Serena: 1 article (01/2022)
6.	Ferger, Boris: 1 article (01/2022)
7.	Han, David: 1 article (01/2022)
8.	Hauber, Wolfgang: 1 article (01/2022)
9.	Khudyakov, Polyna: 1 article (01/2022)
10.	Klinder, Klaus: 1 article (01/2022)

Related Diseases

1.

Schizophrenia (Dementia Praecox)

01/01/2022 - "A phase 1 study to evaluate the safety, tolerability and pharmacokinetics of TAK-041 in healthy participants and patients with stable schizophrenia."
01/01/2022 - "The GPR139 agonist TAK-041 is currently under development for treatment of negative symptoms in schizophrenia which include apathy. "
01/01/2022 - "Further investigation of TAK-041 in individuals with schizophrenia is supported."
01/01/2022 - "TAK-041 was generally well tolerated in healthy volunteers and adults with schizophrenia. "
01/01/2022 - "TAK-041 (NBI-1065846), an orally available, investigational, small molecule agonist of GPR139, an orphan G-protein-coupled receptor, has shown promise in preclinical studies for the treatment of symptoms associated with schizophrenia. "

Related Drugs and Biologics

1.	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)
2.	Antipsychotic Agents (Antipsychotics)

Related Therapies and Procedures

1.	Therapeutics